Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha-1' and Ligand = 'BDBM2579'
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M86PubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of RSK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3DWTPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.126nMAssay Description:Inhibition of human RSK1 using KKLNRTLSVA as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W380MTPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.126nMAssay Description:Inhibition of human RSK1 using KKLNRTLSVA as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5KB8PubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of RSK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4R1DPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of RSK1 (unknown origin) by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K5KPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataKd:  43nMAssay Description:Binding constant for RPS6KA1(Kin.Dom.1 - N-terminal) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataKd:  43nMAssay Description:Binding constant for RSK1(Kin.Dom.1-N-terminal) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataKd:  1.20E+3nMAssay Description:Binding constant for RSK1(Kin.Dom.2-C-terminal) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataKd:  1.20E+3nMAssay Description:Binding constant for RPS6KA1(Kin.Dom.2 - C-terminal) kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed