Compile Data Set for Download or QSAR
Found 32 with Last Name = 'filimonov' and Initial = 'da'
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50367879(LISINOPRIL)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from human blood serumMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130714(1-(3-Mercapto-propionyl)-6-methyl-piperidine-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from bovine kidneyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130714(1-(3-Mercapto-propionyl)-6-methyl-piperidine-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from human blood serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetNeprilysin(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP) from human blood serumMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130714(1-(3-Mercapto-propionyl)-6-methyl-piperidine-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from rat cortex brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP) from rat cortex brain membraneMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130716(CHEMBL322069 | Thioacetic acid S-(2-phenylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from bovine kidneyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130716(CHEMBL322069 | Thioacetic acid S-(2-phenylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from rat cortex brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130716(CHEMBL322069 | Thioacetic acid S-(2-phenylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from human blood serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetNeprilysin(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130716(CHEMBL322069 | Thioacetic acid S-(2-phenylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP) from human blood serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetNeprilysin(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130713(CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP) from human blood serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Aristotle University

LigandPNGBDBM22340((5E)-5-[(3-nitrophenyl)methylidene]-2-(1,3-thiazol...)copy SMILEScopy InChI
Affinity DataIC50: 8.91E+4nMpH: 7.4 T: 2°CAssay Description:The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Aristotle University

LigandPNGBDBM22337((5E)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-...)copy SMILEScopy InChI
Affinity DataIC50: 9.95E+4nMpH: 7.4 T: 2°CAssay Description:The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130715(4-[(Hydroxy-phenethyl-phosphinoylmethyl)-amino]-bu...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from rat cortex brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130713(CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from rat cortex brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130715(4-[(Hydroxy-phenethyl-phosphinoylmethyl)-amino]-bu...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from human blood serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Aristotle University

LigandPNGBDBM22343((5E)-5-[(2-chlorophenyl)methylidene]-2-(1,3-thiazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+5nMpH: 7.4 T: 2°CAssay Description:The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Aristotle University

LigandPNGBDBM22335((5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-thiaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+5nMpH: 7.4 T: 2°CAssay Description:The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Aristotle University

LigandPNGBDBM22341((5E)-5-[(4-chlorophenyl)methylidene]-2-(1,3-thiazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMpH: 7.4 T: 2°CAssay Description:The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Aristotle University

LigandPNGBDBM22338((5E)-5-[(4-methoxyphenyl)methylidene]-2-(1,3-thiaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+5nMpH: 7.4 T: 2°CAssay Description:The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Aristotle University

LigandPNGBDBM22342((5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thiazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+5nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Aristotle University

LigandPNGBDBM22342((5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thiazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+5nMpH: 7.4 T: 2°CAssay Description:The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Aristotle University

LigandPNGBDBM22339((5E)-5-[(4-nitrophenyl)methylidene]-2-(1,3-thiazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+5nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Aristotle University

LigandPNGBDBM22335((5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-thiaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+5nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130713(CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from human blood serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130716(CHEMBL322069 | Thioacetic acid S-(2-phenylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP) from rat cortex brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130713(CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP) from rat cortex brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Aristotle University

LigandPNGBDBM22339((5E)-5-[(4-nitrophenyl)methylidene]-2-(1,3-thiazol...)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+5nMpH: 7.4 T: 2°CAssay Description:The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Aristotle University

LigandPNGBDBM22342((5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thiazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.62E+5nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM27XJPubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130713(CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from bovine kidneyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130714(1-(3-Mercapto-propionyl)-6-methyl-piperidine-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP) from rat cortex brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50130715(4-[(Hydroxy-phenethyl-phosphinoylmethyl)-amino]-bu...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP) from rat cortex brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07512PubMed