Compile Data Set for Download or QSAR
Found 40 with Last Name = 'reddy' and Initial = 'dn'
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human KDAC3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMedDrugBank
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human KDAC6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human KDAC1More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human KDAC6 using acetylated p53 (379 to 382 residues) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human KDAC1 using [3H]acetyl histone H4 peptide substrate incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human KDAC3 using [3H]acetyl histone H4 peptide substrate incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human KDAC6 using [3H]acetyl histone H4 peptide substrate incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148630(CHEMBL3771206)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of human KDAC3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of human KDAC8 preincubated for 15 mins followed by acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of human KDAC8More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of recombinant human KDAC3/NcoR2 using acetylated p53 (379 to 382 residues) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of KDAC3 in human K562 cells using [3H]acetylated histone as substrate incubated for 10 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)copy SMILEScopy InChI
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human KDAC1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of full length human recombinant KDAC3 using fluorophore-conjugated substrate measured as fluorigenic release of 7-amino-4-methylcoumarin ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of KDAC1 in human K562 cells using [3H]acetylated histone as substrate incubated for 10 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148630(CHEMBL3771206)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of human KDAC6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)copy SMILEScopy InChI
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of full length human recombinant KDAC1 using fluorophore-conjugated substrate measured as fluorigenic release of 7-amino-4-methylcoumarin ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of recombinant human KDAC8 using diacetylated p53 (379 to 382 residues) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of recombinant human KDAC1 using acetylated p53 (379 to 382 residues) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148630(CHEMBL3771206)copy SMILEScopy InChI
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of human KDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)copy SMILEScopy InChI
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of human KDAC3 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 4.55E+3nMAssay Description:Inhibition of human KDAC8 using [3H]acetyl histone H4 peptide substrate incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)copy SMILEScopy InChI
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of human KDAC6 preincubated for 15 mins followed by acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148629(CHEMBL3769491)copy SMILEScopy InChI
Affinity DataIC50: 5.07E+3nMAssay Description:Inhibition of recombinant human KDAC6 using FITC-histone 4 acetylated peptide substrate incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148628(CHEMBL3769629)copy SMILEScopy InChI
Affinity DataIC50: 7.66E+3nMAssay Description:Inhibition of recombinant human KDAC6 using FITC-histone 4 acetylated peptide substrate incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)copy SMILEScopy InChI
Affinity DataIC50: 9.29E+3nMAssay Description:Inhibition of full length human recombinant KDAC6 using fluorophore-conjugated substrate measured as fluorigenic release of 7-amino-4-methylcoumarin ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148629(CHEMBL3769491)copy SMILEScopy InChI
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of recombinant human KDAC3 using FITC-p53 acetylated peptide substrate incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human KDAC1 preincubated for 15 mins followed by acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148629(CHEMBL3769491)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of recombinant human KDAC1 using FAM-labelled substrate A incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of KDAC8 in human K562 cells using [3H]acetylated histone as substrate incubated for 10 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of KDAC6 in human K562 cells using [3H]acetylated histone as substrate incubated for 10 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148628(CHEMBL3769629)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human KDAC1 using FAM-labelled substrate A incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148628(CHEMBL3769629)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human KDAC8 using FAM-labelled substrate B incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148629(CHEMBL3769491)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human KDAC8 using FAM-labelled substrate B incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148628(CHEMBL3769629)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human KDAC3 using FITC-p53 acetylated peptide substrate incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human KDAC8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of full length human recombinant KDAC8 using fluorophore-conjugated substrate measured as fluorigenic release of 7-amino-4-methylcoumarin ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50148630(CHEMBL3771206)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human KDAC8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50121210(CHEMBL3622374)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human KDAC6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human KDAC3 preincubated for 15 mins followed by acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB47MPPubMed