Found 65 with Last Name = 'steinberg' and Initial = 'e' TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics SA
Curated by ChEMBL
Domain Therapeutics SA
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics SA
Curated by ChEMBL
Domain Therapeutics SA
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics SA
Curated by ChEMBL
Domain Therapeutics SA
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics SA
Curated by ChEMBL
Domain Therapeutics SA
Curated by ChEMBL
Affinity DataKi: 6.60E+3nMAssay Description:Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics SA
Curated by ChEMBL
Domain Therapeutics SA
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics SA
Curated by ChEMBL
Domain Therapeutics SA
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics SA
Curated by ChEMBL
Domain Therapeutics SA
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Domain Therapeutics SA
Curated by ChEMBL
Domain Therapeutics SA
Curated by ChEMBL
Affinity DataEC50: 1.34E+4nMAssay Description:Positive allosteric modulator activity at human mGluR3 expressed in HEK cells in presence of glutamate EC10 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Domain Therapeutics SA
Curated by ChEMBL
Domain Therapeutics SA
Curated by ChEMBL
Affinity DataEC50: 8.90E+3nMAssay Description:Positive allosteric modulator activity at human mGluR3 expressed in HEK cells in presence of glutamate EC10 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Domain Therapeutics SA
Curated by ChEMBL
Domain Therapeutics SA
Curated by ChEMBL
Affinity DataEC50: 1.04E+4nMAssay Description:Positive allosteric modulator activity at human mGluR3 expressed in HEK cells in presence of glutamate EC10 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.25E+3nMAssay Description:Inhibitory activity against human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:The compound was tested for the inhibition of human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 3.96E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 310nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 1.27E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 280nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 860nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 2.47E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 1.74E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 3.01E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 9.84E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 750nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 1.01E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 1.72E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 1.39E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 690nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 106nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 165nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 1.71E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 2.34E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 46nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing chimeric G protein assessed as increase in...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Prexton Therapeutics
Curated by ChEMBL
Prexton Therapeutics
Curated by ChEMBL
Affinity DataEC50: 27nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
Affinity DataEC50: 79nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Prexton Therapeutics
Curated by ChEMBL
Prexton Therapeutics
Curated by ChEMBL
Affinity DataEC50: 47nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
