Compile Data Set for Download or QSAR
Found 20 with Last Name = 'mengod' and Initial = 'g'
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385902(CHEMBL2041596)copy SMILEScopy InChI
Affinity DataKi:  5.91E+3nMAssay Description:Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385903(CHEMBL2041614)copy SMILEScopy InChI
Affinity DataKi:  7.22E+3nMAssay Description:Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50277784(CHEMBL484928 | N,N,2-trimethyl-5-nitrobenzenesulfo...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385909(CHEMBL2041586)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of PDE7A1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM77437(1-({[5-(ethoxycarbonyl)-4-methyl-1,3-thiazol-2-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibition of PDE7A1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385910(CHEMBL2041587)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Inhibition of PDE7A1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385906(CHEMBL2041597)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385906(CHEMBL2041597)copy SMILEScopy InChI
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385903(CHEMBL2041614)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385908(CHEMBL2041604)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385903(CHEMBL2041614)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385902(CHEMBL2041596)copy SMILEScopy InChI
Affinity DataIC50: 5.17E+3nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385907(CHEMBL2041602)copy SMILEScopy InChI
Affinity DataIC50: 7.31E+3nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385905(CHEMBL2041590)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385902(CHEMBL2041596)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human recombinant PDE4B2 using fluorscein 3',5'-cyclic phosphate after 60 mins by IMAP fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385908(CHEMBL2041604)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385904(CHEMBL2041589)copy SMILEScopy InChI
Affinity DataIC50: 3.34E+4nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385902(CHEMBL2041596)copy SMILEScopy InChI
Affinity DataIC50: 5.46E+4nMAssay Description:Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385902(CHEMBL2041596)copy SMILEScopy InChI
Affinity DataIC50: 6.63E+4nMAssay Description:Inhibition of human recombinant PDE4D3 using fluorscein 3',5'-cyclic phosphate after 60 mins by IMAP fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)

Curated by ChEMBL
LigandPNGBDBM50385905(CHEMBL2041590)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XJBPubMed