Found 2 Enz. Inhib. hit(s) with Target = 'High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A' and Ligand = 'BDBM50385903' TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
Affinity DataKi: 7.22E+3nMAssay Description:Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
Instituto de Qu£mica M£dica (CSIC)
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
