Compile Data Set for Download or QSAR
Found 206 with Last Name = 'rhodes' and Initial = 'g'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054826(CHEMBL144474 | [7-([4,4']Bipiperidinyl-1-carbonyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054827(CHEMBL85094 | SB-208651 | {8-[(4-Carbamimidoyl-phe...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054830(CHEMBL356986 | [(R)-7-([4,4']Bipiperidinyl-1-carbo...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036089(CHEMBL18288 | [8-(4-Carbamimidoyl-phenylcarbamoyl)...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036088(CHEMBL18734 | [(6S,13S)-13-(3-Guanidino-propyl)-14...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054831(CHEMBL143219 | [7-([4,4']Bipiperidinyl-1-carbonyl)...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054824(CHEMBL144681 | {7-[Methyl-(3-piperidin-4-yl-propyl...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054829(CHEMBL306110 | [7-(3-Carbamimidoyl-phenylcarbamoyl...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054828(CHEMBL143394 | {7-[(3-Carbamimidoyl-phenyl)-methyl...)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9H16PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054825(CHEMBL356301 | [(S)-7-([4,4']Bipiperidinyl-1-carbo...)copy SMILEScopy InChI
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157059((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-phenyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157055((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157057((S)-2-Methoxy-3-{4-[5-(4-phenoxy-phenoxy)-pent-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157058((S)-2-Methoxy-3-{3-methoxy-4-[3-(4-phenoxy-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157060((S)-2-Methoxy-3-{4-[4-(4-phenoxy-phenoxy)-but-1-yn...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195711(3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-((...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157061((S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-phenyl}-2-...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195708(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195716(3-{4-[2-(2-biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195714(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157056((S)-2-Methoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157054((S)-2-Ethoxy-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195702(3-[4-[2-(2-biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195715(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195713(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195711(3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-((...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195707(3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-((...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195710(3-(2-((benzyloxycarbonyl)methyl)-4-(2-(5-methyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50563816(Eleclazine | GS-6615)copy SMILES
Affinity DataIC50: 100nMAssay Description:Inhibition of NaV1.5 expressed in human HEK293 cells assessed as inhibition of late sodium current at -80 mV resting membrane potential by electrophy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36DMPubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50563816(Eleclazine | GS-6615)copy SMILES
Affinity DataIC50: 100nMAssay Description:Inhibition of NaV1.5 expressed in human HEK293 cells assessed as inhibition of late sodium current at 3 Hz frequency by manual patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36DMPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195714(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195712(3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-((...)copy SMILEScopy InChI
Affinity DataIC50: 161nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50563816(Eleclazine | GS-6615)copy SMILES
Affinity DataIC50: 260nMAssay Description:Inhibition of NaV1.5 expressed in human HEK293 cells assessed as inhibition of late sodium current at 1 Hz frequency by manual patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36DMPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50157055((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 309nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50447466(CHEMBL3115191)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270M7PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50447393(CHEMBL3114722)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639R75PubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195710(3-(2-((benzyloxycarbonyl)methyl)-4-(2-(5-methyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 441nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195716(3-{4-[2-(2-biphenyl-4-yl-5-methyl-oxazol-4-yl)-eth...)copy SMILEScopy InChI
Affinity DataIC50: 449nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50157059((S)-3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-phenyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50195715(3-(2-((isopropoxycarbonyl)methyl)-4-(2-(5-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 516nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50157061((S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-phenyl}-2-...)copy SMILEScopy InChI
Affinity DataIC50: 568nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50563816(Eleclazine | GS-6615)copy SMILES
Affinity DataIC50: 600nMAssay Description:Inhibition of NaV1.5 expressed in human HEK293 cells assessed as inhibition of late sodium current at -120 mV resting membrane potential by electroph...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36DMPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50447469(CHEMBL3115185)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270M7PubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50563816(Eleclazine | GS-6615)copy SMILES
Affinity DataIC50: 600nMAssay Description:Inhibition of NaV1.5 expressed in human HEK293 cells assessed as inhibition of late sodium current at 0.1 Hz frequency by manual patch clamp techniqu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ36DMPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195709(3-(2-((3-benzylureido)methyl)-4-(2-(5-methyl-2-phe...)copy SMILEScopy InChI
Affinity DataIC50: 706nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FSCPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly and Co

Curated by ChEMBL
LigandPNGBDBM50157057((S)-2-Methoxy-3-{4-[5-(4-phenoxy-phenoxy)-pent-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B30T6PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50447472(CHEMBL3115177)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270M7PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50447467(CHEMBL3115188)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270M7PubMed
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