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Found 243 with Last Name = 'wennerstal' and Initial = 'gm'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189904(US10227346, Example 29 | US10426135, Example 29 | ...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189904(US10227346, Example 29 | US10426135, Example 29 | ...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411418(N-(3-((3R,4R)-1-((R)-2-cyclopentylpropanoyl)- 3-me...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411419(N-(3-((3R,4R)-1-((R)-2-cyclopentylpropanoyl)- 3-me...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411412((R)-2-fluoro-N-(1-methyl-3-(1-(2,3,3- trimethylbut...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411417(N-(3-((3R,4R)-1-((R)-2-cyclopentylpropanoyl)- 3-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM190325(US10227346, Example 81 | US10426135, Example 81 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM190325(US10227346, Example 81 | US10426135, Example 81 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411410((R)-1,3,5-trimethyl-N-(1-methyl-3-(1-(2,3,3- trime...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189884(US10227346, Example 11 | US10426135, Example 11 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189884(US10227346, Example 11 | US10426135, Example 11 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411411((R)-2-ethoxy-N-(1-methyl-3-(1-(2,3,3- trimethylbut...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411409((R)-4-methyl-N-(1-methyl-3-(1-(2,3,3- trimethylbut...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM368656(3-cyano-N-(3-((1R,5S,8r)-3-isobutyryl-3- azabicycl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM368656(3-cyano-N-(3-((1R,5S,8r)-3-isobutyryl-3- azabicycl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411415((R)-N-(3-(1-(2-(bicyclo[1.1.1]pentan-1- yl)propano...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411416(N-(3-((3R,4R)-1-((R)-2-cyclopentylpropanoyl)- 3-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM190346(US10227346, Example 95 | US10426135, Example 95 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189895(US10227346, Example 22 | US10426135, Example 22 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM190346(US10227346, Example 95 | US10426135, Example 95 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189895(US10227346, Example 22 | US10426135, Example 22 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189905(US10227346, Example 30 | US10426135, Example 30 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189905(US10227346, Example 30 | US10426135, Example 30 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411400((S)-N-(3-(1-(2,3-dimethylbutanoyl)pipendin-4-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189874(US10227346, Example 3 | US10426135, Example 3 | US...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189874(US10227346, Example 3 | US10426135, Example 3 | US...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189882(US10227346, Example 10 | US10426135, Example 10 | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189882(US10227346, Example 10 | US10426135, Example 10 | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411403((R)-N-(3-(1-(cyclopentanecarbonyl)-2,2-dimethylpip...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189891(US10227346, Example 18 | US10426135, Example 18 | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189891(US10227346, Example 18 | US10426135, Example 18 | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189888(US10227346, Example 15 | US10426135, Example 15 | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189888(US10227346, Example 15 | US10426135, Example 15 | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189873(US10227346, Example 2 | US10426135, Example 2 | US...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189873(US10227346, Example 2 | US10426135, Example 2 | US...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM190324(US10227346, Example 80 | US10426135, Example 80 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM190324(US10227346, Example 80 | US10426135, Example 80 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189918(US10227346, Example 41 | US10426135, Example 41 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM368615(US10227346, Example 36 | US10426135, Example 36)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189918(US10227346, Example 41 | US10426135, Example 41 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM368615(US10227346, Example 36 | US10426135, Example 36)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM411391((R)-N-(3-(1-(2-cyclopentylpropanoyl)piperidin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:In general, the assay is based on the interaction between N-terminally Six-Histidine-tagged-RORC2 ligand binding domain (6-His-RORC2 LBD), expressed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5B40US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189936(US10227346, Example 54 | US10426135, Example 54 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189897(US10227346, Example 23 | US10426135, Example 23 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189936(US10227346, Example 54 | US10426135, Example 54 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189897(US10227346, Example 23 | US10426135, Example 23 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189879(US10227346, Example 7 | US10426135, Example 7 | US...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189879(US10227346, Example 7 | US10426135, Example 7 | US...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189894(US10227346, Example 21 | US10426135, Example 21 | ...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189894(US10227346, Example 21 | US10426135, Example 21 | ...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
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