Found 510 with Last Name = 'waldschmidt' and Initial = 'h' TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 11nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 11nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 12nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 17nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 21nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 21nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 23nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 23nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 50nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 50nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 57nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 57nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 60nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 61nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 69nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 69nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 70nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 78nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 84nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 97nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 97nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 100nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of GRK1 (unknown origin) using tubulin as substrate by SDS-PAGE methodMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 110nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 120nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Displacement of BODIPY TR-ADP from bovine GRK1 (1 to 535 residues) preincubated for 10 mins followed by compound addition and measured after 10 to 15...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 130nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 130nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 140nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 150nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 150nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 150nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 180nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 190nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 190nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 200nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 200nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
US Patent
Affinity DataIC50: 200nMAssay Description:Rho-associated coiled-coil kinase (ROCK) assays were performed with the ADP-Glo system using 0.1 μg ROCK1 and 1 μg S6K substrate, and 100 &...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
