Compile Data Set for Download or QSAR
Found 162 with Last Name = 'li' and Initial = 'hf'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095261((3-Chloro-phenyl)-(6,7-diethoxy-quinazolin-4-yl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3556(4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline |...)copy SMILEScopy InChI
Affinity DataIC50: 0.410nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095273((6,7-Diethoxy-quinazolin-4-yl)-(3-iodo-phenyl)-ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.640nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)copy SMILEScopy InChI
Affinity DataIC50: 0.660nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3533(CHEMBL1204305 | CHEMBL96065 | N-(3-iodophenyl)-6,7...)copy SMILEScopy InChI
Affinity DataIC50: 1.05nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095261((3-Chloro-phenyl)-(6,7-diethoxy-quinazolin-4-yl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)copy SMILEScopy InChI
Affinity DataIC50: 1.26nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM26041(2-chloro-5-(2-phenyl-5-(pyridin-4-yl)-1H-imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3556(4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline |...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095273((6,7-Diethoxy-quinazolin-4-yl)-(3-iodo-phenyl)-ami...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139601(1-(4-bromo-3-(trifluoromethyl)phenyl)-3-(4-(2-(met...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8KJ5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139601(1-(4-bromo-3-(trifluoromethyl)phenyl)-3-(4-(2-(met...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375259(CHEMBL220019)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3531(CHEMBL541586 | CHEMBL94431 | N-(3-fluorophenyl)-6,...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3533(CHEMBL1204305 | CHEMBL96065 | N-(3-iodophenyl)-6,7...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095277((6,7-Diethoxy-quinazolin-4-yl)-(3-fluoro-phenyl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370935(CHEMBL1203937)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375258(CHEMBL219870)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095277((6,7-Diethoxy-quinazolin-4-yl)-(3-fluoro-phenyl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 8.17nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370943(CHEMBL1203935)copy SMILEScopy InChI
Affinity DataIC50: 8.95nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370938(CHEMBL1203939)copy SMILEScopy InChI
Affinity DataIC50: 9.31nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375252(CHEMBL218932)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50177114(CHEMBL1203938 | CHEMBL374810 | cid_1474879)copy SMILEScopy InChI
Affinity DataIC50: 10.9nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50132260(2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmetho...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8KJ5PubMedDrugBank
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM4619(Anilinoquinazoline deriv. 2 | CHEMBL1204360 | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 12.8nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375257(CHEMBL403732)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370938(CHEMBL1203939)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370934(CHEMBL1203940)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370935(CHEMBL1203937)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370942(CHEMBL1203936)copy SMILEScopy InChI
Affinity DataIC50: 19.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370944(CHEMBL1203934)copy SMILEScopy InChI
Affinity DataIC50: 19.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370942(CHEMBL1203936)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50077961(3-(2-Phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370934(CHEMBL1203940)copy SMILEScopy InChI
Affinity DataIC50: 23.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085418(3-(3,5-dibromo-4-hydroxybenzylidene)-5-(cyclopropa...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139614(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8KJ5PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3531(CHEMBL541586 | CHEMBL94431 | N-(3-fluorophenyl)-6,...)copy SMILEScopy InChI
Affinity DataIC50: 31.9nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085413(3-(3,5-dichloro-4-hydroxybenzylidene)-5-phenylindo...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM4619(Anilinoquinazoline deriv. 2 | CHEMBL1204360 | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 32.2nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375261(CHEMBL219745)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249245(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8KJ5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085411(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X29S8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50177114(CHEMBL1203938 | CHEMBL374810 | cid_1474879)copy SMILEScopy InChI
Affinity DataIC50: 47.7nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3556(4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline |...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370943(CHEMBL1203935)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TT6PubMed
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