Compile Data Set for Download or QSAR
Found 114 with Last Name = 'fraser' and Initial = 'hl'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161957(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(p...)copy SMILEScopy InChI
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50161957(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(p...)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human EGFR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209886((2E)-4-(dimethylamino)-N-[7-ethoxy-4-({4-[(3-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209878((2E)-N-[4-({4-[(3-chlorobenzyl)oxy]-3,6-dioxocyclo...)copy SMILEScopy InChI
Affinity DataIC50: 12.2nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209879((2E)-N-(4-{[4-(benzyloxy)-3,6-dioxocyclohexa-1,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 18.7nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32447(Benzo[c][2,7]naphthyridine, 39)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209883((2E)-4-(dimethylamino)-N-[7-ethoxy-4-({4-[(3-methy...)copy SMILEScopy InChI
Affinity DataIC50: 24.9nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32435(Benzo[c][2,7]naphthyridine, 28)copy SMILEScopy InChI
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 27.3nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32450(Benzo[c][2,7]naphthyridine, 42)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)copy SMILEScopy InChI
Affinity DataIC50: 34.9nMAssay Description:Inhibition of human EGFR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32430(Benzo[c][2,7]naphthyridine, 24)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209878((2E)-N-[4-({4-[(3-chlorobenzyl)oxy]-3,6-dioxocyclo...)copy SMILEScopy InChI
Affinity DataIC50: 35.6nMAssay Description:Inhibition of human EGFR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32433(Benzo[c][2,7]naphthyridine, 14)copy SMILEScopy InChI
Affinity DataIC50: 43nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209886((2E)-4-(dimethylamino)-N-[7-ethoxy-4-({4-[(3-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 43.1nMAssay Description:Inhibition of human EGFR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209877(2-(3-fluorobenzyloxy)-5-(6-methoxy-7-(2-methoxyeth...)copy SMILEScopy InChI
Affinity DataIC50: 46.1nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32444(Benzo[c][2,7]naphthyridine, 36)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209884((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(2-thien...)copy SMILEScopy InChI
Affinity DataIC50: 47.5nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209882(2-(3-methoxybenzyloxy)-5-(6-methoxy-7-(2-methoxyet...)copy SMILEScopy InChI
Affinity DataIC50: 50.2nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32449(Benzo[c][2,7]naphthyridine, 41)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209888(2-(benzyloxy)-5-(6-methoxy-7-(2-methoxyethoxy)quin...)copy SMILEScopy InChI
Affinity DataIC50: 53.7nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32436(Benzo[c][2,7]naphthyridine, 29)copy SMILEScopy InChI
Affinity DataIC50: 57nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32437(Benzo[c][2,7]naphthyridine, 30)copy SMILEScopy InChI
Affinity DataIC50: 65nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32427(Benzo[c][2,7]naphthyridine, 21)copy SMILEScopy InChI
Affinity DataIC50: 66nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32445(Benzo[c][2,7]naphthyridine, 37)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32422(Benzo[c][2,7]naphthyridine, 9)copy SMILEScopy InChI
Affinity DataIC50: 70nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32431(Benzo[c][2,7]naphthyridine, 25)copy SMILEScopy InChI
Affinity DataIC50: 74nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32441(Benzo[c][2,7]naphthyridine, 33)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209884((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(2-thien...)copy SMILEScopy InChI
Affinity DataIC50: 76.2nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209878((2E)-N-[4-({4-[(3-chlorobenzyl)oxy]-3,6-dioxocyclo...)copy SMILEScopy InChI
Affinity DataIC50: 80.2nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209885((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 90.8nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32448(Benzo[c][2,7]naphthyridine, 40)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human EGFR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32425(Benzo[c][2,7]naphthyridine, 12)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32428(Benzo[c][2,7]naphthyridine, 22)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209879((2E)-N-(4-{[4-(benzyloxy)-3,6-dioxocyclohexa-1,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 102nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209875((2E)-4-(dimethylamino)-N-[7-ethoxy-4-({4-[(3-metho...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32423(Benzo[c][2,7]naphthyridine, 10)copy SMILEScopy InChI
Affinity DataIC50: 108nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209881((2E)-4-(dimethylamino)-N-[7-ethoxy-4-({4-[2-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 109nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209880((2E)-N-[4-({4-[(3,4-difluorobenzyl)oxy]-3,6-dioxoc...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209886((2E)-4-(dimethylamino)-N-[7-ethoxy-4-({4-[(3-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209885((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 135nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209888(2-(benzyloxy)-5-(6-methoxy-7-(2-methoxyethoxy)quin...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human VEGFR2 in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32446(Benzo[c][2,7]naphthyridine, 38)copy SMILEScopy InChI
Affinity DataIC50: 142nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32434(Benzo[c][2,7]naphthyridine, 27)copy SMILEScopy InChI
Affinity DataIC50: 144nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32432(Benzo[c][2,7]naphthyridine, 26)copy SMILEScopy InChI
Affinity DataIC50: 146nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
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