Compile Data Set for Download or QSAR
Found 114 with Last Name = 'dahse' and Initial = 'hm'
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103281(1-(3-Benzoyl-4-diphenylacetylamino-phenylcarbamoyl...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50216095(5-(4-cyclohexylthiosemicarbazono)methyl-2-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103269(1-{3-Benzoyl-4-[2-(4-bromo-phenyl)-acetylamino]-ph...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103285(1-[3-Benzoyl-4-(2-p-tolyl-acetylamino)-phenylcarba...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50134329(CHEMBL122708 | Sulfamic acid (11R,12S,15S,16S)-13-...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103271(1-(3-Benzoyl-4-phenylmethanesulfonylamino-phenylca...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103280(1-(3-Benzoyl-4-p-tolylmethanesulfonylamino-phenylc...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103262(1-{3-Benzoyl-4-[2-(4-chloro-phenyl)-acetylamino]-p...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103274(1-{3-Benzoyl-4-[2-(4-nitro-phenyl)-acetylamino]-ph...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103261(1-{3-Benzoyl-4-[2-(2,4-dichloro-phenyl)-acetylamin...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50216114(3-(4-cyclohexylthiosemicarbazono)methyl-2-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50216102(3-(4-cyclohexylthiosemicarbazono)methyl-4-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103270(1-{3-Benzoyl-4-[2-(2,6-dichloro-phenyl)-acetylamin...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103272(1-[3-Benzoyl-4-(2-naphthalen-1-yl-acetylamino)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103260(1-[3-Benzoyl-4-(2-o-tolyl-acetylamino)-phenylcarba...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103258(1-{3-Benzoyl-4-[2-(2,3-dichloro-phenyl)-acetylamin...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50216115(3-((cyclohexylaminocarbonothioyl)hydrazono]methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103277(1-[3-Benzoyl-4-(2-naphthalen-2-yl-acetylamino)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103284(1-{3-Benzoyl-4-[2-(3,4-dichloro-phenyl)-acetylamin...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103276(1-{3-Benzoyl-4-[2-(3,5-dichloro-phenyl)-acetylamin...)copy SMILEScopy InChI
Affinity DataIC50: 535nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103259(1-[3-Benzoyl-4-(2-m-tolyl-acetylamino)-phenylcarba...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103268(1-{3-Benzoyl-4-[2-(4-methoxy-phenyl)-acetylamino]-...)copy SMILEScopy InChI
Affinity DataIC50: 545nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103257(1-[3-Benzoyl-4-(4-carboxy-butyrylamino)-phenylcarb...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103287(1-(3-Benzoyl-4-phenylacetylamino-phenylcarbamoyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103278(1-[3-Benzoyl-4-(2-phenyl-propionylamino)-phenylcar...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universität Bayreuth

Curated by ChEMBL
LigandPNGBDBM50276581((+/-)-wiedendiol B | CHEMBL456619)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B02BXPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103266(1-[3-Benzoyl-4-(3-carboxy-propionylamino)-phenylca...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103283(1-{3-Benzoyl-4-[2-(4-trifluoromethyl-phenyl)-acety...)copy SMILEScopy InChI
Affinity DataIC50: 725nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50216125(6-(4-cyclohexylthiosemicarbazono)methyl-2-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50216126(3-(1H-tetrazol-5-yl)-benzaldehyde cyclohexylthiose...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Hans Knöll Institute

LigandPNGBDBM179812(Myxochelin J7)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2105RPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103282(1-[3-Benzoyl-4-(3-phenyl-propionylamino)-phenylcar...)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50216119(3-(4-cyclohexylthiosemicarbazono)methylbenzoic aci...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103256(1-[3-Benzoyl-4-(2-oxo-2-phenyl-acetylamino)-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Hans Knöll Institute

LigandPNGBDBM179811(Myxochelin J6)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+3nMAssay Description:Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2105RPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Hans Knöll Institute

LigandPNGBDBM179808(Myxochelin J3)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+3nMAssay Description:Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2105RPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Hans Knöll Institute

LigandPNGBDBM179805(Myxochelin A)copy SMILEScopy InChI
Affinity DataIC50: 1.72E+3nMAssay Description:Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2105RPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103263(1-[3-Benzoyl-4-(3-methoxycarbonyl-propionylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Hans Knöll Institute

LigandPNGBDBM50080463(CHEMBL3422317)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 DE3 assessed as reduction in 5-LO product formation pre-incubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9CGPPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103267(1-[3-Benzoyl-4-(2-biphenyl-4-yl-acetylamino)-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50216127(4-(4-cyclohexylthiosemicarbazono)methyl-phenol | C...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Hans Knöll Institute

LigandPNGBDBM179807(Myxochelin J2)copy SMILEScopy InChI
Affinity DataIC50: 2.39E+3nMAssay Description:Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2105RPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103264(1-[3-Benzoyl-4-(4-methoxycarbonyl-butyrylamino)-ph...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Philipps-Universität Marburg

Curated by ChEMBL
LigandPNGBDBM50103273(1-{3-Benzoyl-4-[2-(2,5-dichloro-phenyl)-acetylamin...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60TBPubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM50216094((E,Z)-2-(4-cyclohexylthiosemicarbazono)methyl-6-hy...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Institute for Natural Products Research and Infection Biology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Estrone sulfatase in human placental microsomeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z45PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Hans Knöll Institute

LigandPNGBDBM179806(Myxochelin J1)copy SMILEScopy InChI
Affinity DataIC50: 3.15E+3nMAssay Description:Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2105RPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Hans Knöll Institute

LigandPNGBDBM179809(Myxochelin J4)copy SMILEScopy InChI
Affinity DataIC50: 3.54E+3nMAssay Description:Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2105RPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Hans Knöll Institute

LigandPNGBDBM179813(Myxochelin J8)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2105RPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Hans Knöll Institute

LigandPNGBDBM179819(Myxochelin J14)copy SMILEScopy InChI
Affinity DataIC50: 3.64E+3nMAssay Description:Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2105RPubMed
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