Compile Data Set for Download or QSAR
Found 371 with Last Name = 'waldschmidt' and Initial = 'hv'
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173310(CHEMBL3808660 | US10023564, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173307(CHEMBL3809796 | US10023564, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50173313(CHEMBL1738878)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50173313(CHEMBL1738878)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173315(CHEMBL3809100 | US10023564, Example 4)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173305(CHEMBL3810107 | US10023564, Example 3)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50257350(CHEMBL1738877)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50260141(CHEMBL4097393)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M047XQPubMed
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50260140(CHEMBL4090144)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50257350(CHEMBL1738877)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173311(CHEMBL3810073 | US10023564, Example 6)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173325(CHEMBL3809965 | US10023564, Example 5)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173314(CHEMBL3808840 | US10023564, Example 16)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173306(CHEMBL3808565 | US10023564, Example 7)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173312(CHEMBL3810312 | US10023564, Example 18)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173320(GSK-180736A | GSK180736A | US10023564, Compound GS...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetRhodopsin kinase GRK1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173307(CHEMBL3809796 | US10023564, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of GRK1 (unknown origin) using tubulin as substrate by SDS-PAGE methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173323(CHEMBL3808621 | US10023564, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50173319(CHEMBL3809020 | US10023564, Example 11)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
TargetRhodopsin kinase GRK1(Bos taurus)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50265871(3-(2-(1-(2-(dimethylamino)acetyl)-6-methoxy-4,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Displacement of BODIPY TR-ADP from bovine GRK1 (1 to 535 residues) preincubated for 10 mins followed by compound addition and measured after 10 to 15...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50173319(CHEMBL3809020 | US10023564, Example 11)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of GRK2 (unknown origin)More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173329(CHEMBL3809697 | US10023564, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM283997(E23 | US10023564, Example 23)copy SMILES
Affinity DataIC50: 160nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM283996(E22 | US10023564, Example 22)copy SMILES
Affinity DataIC50: 160nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173316(CHEMBL3810250)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50461305(CHEMBL4225917)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173324(CHEMBL3809124 | US10023564, Example 30)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50529465(CHEMBL4464632)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HR8PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50529470(CHEMBL4475305)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 0 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HR8PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM283998(E24 | US10023564, Example 24)copy SMILES
Affinity DataIC50: 250nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM283998(E24 | US10023564, Example 24)copy SMILES
Affinity DataIC50: 260nMAssay Description:Inhibition of GRK5 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50529470(CHEMBL4475305)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 30 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HR8PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50529470(CHEMBL4475305)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 60 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HR8PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173328(CHEMBL3808918 | US10023564, Example 14)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50529469(CHEMBL4456539)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 30 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HR8PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50461327(CHEMBL4227081)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50529469(CHEMBL4456539)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 60 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HR8PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM283996(E22 | US10023564, Example 22)copy SMILES
Affinity DataIC50: 380nMAssay Description:Inhibition of GRK5 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50173310(CHEMBL3808660 | US10023564, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of GRK5 (unknown origin) using tubulin as substrate by SDS-PAGE methodMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50260143(CHEMBL4087244)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M047XQPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173326(CHEMBL3809604 | US10023564, Example 29)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM284001(E27 | US10023564, Example 27)copy SMILES
Affinity DataIC50: 400nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50461315(CHEMBL4225489)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173327(CHEMBL3808499 | US10023564, Example 28)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM284006(E32 | US10023564, Example 32)copy SMILES
Affinity DataIC50: 460nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50461319(CHEMBL4225645)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50461321(CHEMBL4227138)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z1868PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173317(CHEMBL3810349 | US10023564, Example 12)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of ROCK1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ12X4PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50529469(CHEMBL4456539)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 0 mins by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3HR8PubMed
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
Department of Medicinal Chemistry, College of Pharmacy,?Departments of Pharmacology and Biological Chemistry, Life Sciences Institute,§Ph.D. Program in Chemical Biology,?Vahlteich Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50260139(CHEMBL4075712)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M047XQPubMed
Displayed 1 to 50 (of 371 total ) | Next | Last >>
Jump to: