Compile Data Set for Download or QSAR
Found 151 with Last Name = 'briand' and Initial = 'j'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359016(CHEMBL1924017)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359013(CHEMBL1924014)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359018(CHEMBL1924019)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359032(CHEMBL1924024)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359017(CHEMBL1924018)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359022(CHEMBL1924023)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359012(CHEMBL1924013)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359023(CHEMBL1170725)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359015(CHEMBL1924016)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359025(CHEMBL1924005)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359024(CHEMBL1924004)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359014(CHEMBL1924015)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359024(CHEMBL1924004)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359020(CHEMBL1924021)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359021(CHEMBL1924022)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359026(CHEMBL1924006)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359019(CHEMBL1924020)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359033(CHEMBL1924012)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359025(CHEMBL1924005)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359027(CHEMBL1924007)copy SMILEScopy InChI
Affinity DataKi:  79nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359028(CHEMBL1924008)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359029(CHEMBL1924009)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359026(CHEMBL1924006)copy SMILEScopy InChI
Affinity DataKi:  251nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359031(CHEMBL1924011)copy SMILEScopy InChI
Affinity DataKi:  631nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359030(CHEMBL1924010)copy SMILEScopy InChI
Affinity DataKi:  794nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359028(CHEMBL1924008)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359027(CHEMBL1924007)copy SMILEScopy InChI
Affinity DataKi:  1.26E+3nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359023(CHEMBL1170725)copy SMILEScopy InChI
Affinity DataKi:  1.26E+3nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359030(CHEMBL1924010)copy SMILEScopy InChI
Affinity DataKi:  1.59E+3nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359029(CHEMBL1924009)copy SMILEScopy InChI
Affinity DataKi:  2.51E+3nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50359031(CHEMBL1924011)copy SMILEScopy InChI
Affinity DataKi:  2.51E+3nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs in prese...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9C6DPubMed
TargetHexokinase-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169013(CHEMBL3805703)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMAssay Description:Competitive inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) assessed as formation of G6P by continuou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
LigandPNGBDBM50502640(CHEMBL4470585)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human TRPV4More data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
GlaxoSmithKline

LigandPNGBDBM119133((S)-4-(4-(Benzofuran-5-yl)phenyl)-3-((1-(cycloprop...)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of FAS by GSK2194069 was measured by an endpoint assay for thiols using a fluorescent maleimide.More data for this Ligand-Target Pair
TargetHexokinase-1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169038(CHEMBL3804841)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169033(CHEMBL3806069)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169042(CHEMBL3806103)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169037(CHEMBL3805205)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169026(CHEMBL3805148)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169037(CHEMBL3805205)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169032(CHEMBL3805398)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169041(CHEMBL3805653)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169038(CHEMBL3804841)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169031(CHEMBL3805905)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169034(CHEMBL3805734)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169031(CHEMBL3805905)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169039(CHEMBL3806132)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169017(CHEMBL3804930)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169043(CHEMBL3806095)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
TargetHexokinase-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169034(CHEMBL3805734)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XWWPubMed
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