Compile Data Set for Download or QSAR
Found 320 with Last Name = 'andrez' and Initial = 'jc'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145281(US8952169, 60 | US9771376, Example 60)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145285(US8952169, 64 | US9771376, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of full length human Nav1.7 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70937(US9546164, 100 | US9694002, 100)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of full length human Nav1.7 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM47139(US8952169, 175 | US8952169, 295)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM71064(US9546164, 209 | US9694002, 209)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145285(US8952169, 64 | US9771376, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145369(US8952169, 148 | US9771376, Example 148)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145281(US8952169, 60 | US9771376, Example 60)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70937(US9546164, 100 | US9694002, 100)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70936(US9546164, 99 | US9694002, 99)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
In DepthDetails
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145375(US8952169, 154)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145376(US8952169, 155)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70987(US9546164, 139 | US9694002, 139)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
LigandPNGBDBM145466(US8952169, 245)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145466(US8952169, 245)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145374(US8952169, 153)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70937(US9546164, 100 | US9694002, 100)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length human Nav1.4 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50587016(CHEMBL5091342)copy SMILES
Affinity DataIC50: 3.60nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50587015(CHEMBL5082739)copy SMILES
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50615672(CHEMBL5272143)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145635(US8952169, 440)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145281(US8952169, 60 | US9771376, Example 60)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145227(US8952169, 6 | US9771376, Example 6)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145382(US8952169, 161)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145623(US8952169, 426)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145466(US8952169, 245)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145266(US8952169, 45)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70981(US9546164, 135 | US9694002, 135)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145374(US8952169, 153)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145438(US8952169, 217)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145285(US8952169, 64 | US9771376, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Inhibition of full length human Nav1.4 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
LigandPNGBDBM145466(US8952169, 245)copy SMILEScopy InChI
In DepthDetails
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM71126(US9546164, 253 | US9694002, 253)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50615671(CHEMBL5279943)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145623(US8952169, 426)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145285(US8952169, 64 | US9771376, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of full length human Nav1.1 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145373(US8952169, 152 | US9771376, Example 152)copy SMILEScopy InChI
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel subunit beta-1(Homo sapiens)
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50530536(CHEMBL4580996 | US11174268, Example 336)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32344PubMed
TargetSodium channel subunit beta-1(Homo sapiens)
Xenon Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50530536(CHEMBL4580996 | US11174268, Example 336)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z32344PubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145369(US8952169, 148 | US9771376, Example 148)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 1 hr in presence of veratridine by sodium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145266(US8952169, 45)copy SMILEScopy InChI
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145387(US8952169, 166 | US9771376, Example 166)copy SMILEScopy InChI
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145591(US8952169, 389)copy SMILEScopy InChI
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145466(US8952169, 245)copy SMILEScopy InChI
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70937(US9546164, 100 | US9694002, 100)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 1 hr in presence of veratridine by sodium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
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