Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 7 subunit alpha' and Ligand = 'BDBM70937'
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70937(US9546164, 100 | US9694002, 100)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of full length human Nav1.7 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70937(US9546164, 100 | US9694002, 100)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70937(US9546164, 100 | US9694002, 100)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 1 hr in presence of veratridine by sodium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed