Compile Data Set for Download or QSAR
Found 165 with Last Name = 'wright' and Initial = 'je'
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50068808(CHEMBL297088 | N-(4-Carboxy-4-{4-[(2,4-diamino-qui...)copy SMILEScopy InChI
Affinity DataKi:  0nMAssay Description:Compound was evaluated for the inhibition of Dihydrofolate reductase at concentration ranged from 0.15-0.50 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542P85PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50068813(CHEMBL149962 | N-(4-Carboxy-4-{4-[(2,4-diamino-pyr...)copy SMILEScopy InChI
Affinity DataKi:  0nMAssay Description:Compound was evaluated for the inhibition of Dihydrofolate reductase at concentration ranged from 0.15-0.50 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542P85PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011320(CHEMBL18155 | N-(4-Carboxy-4-{4-[(2,4-diamino-pter...)copy SMILEScopy InChI
Affinity DataKi:  0nMAssay Description:Compound was evaluated for the inhibition of Dihydrofolate reductase at concentration ranged from 0.15-0.50 uMMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50068810(CHEMBL149164 | N-(4-Carboxy-4-{4-[(2,4-diamino-pyr...)copy SMILEScopy InChI
Affinity DataKi:  0nMAssay Description:Compound was evaluated for the inhibition of Dihydrofolate reductase at concentration ranged from 0.15-0.50 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542P85PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50068812(CHEMBL146917 | N-(4-Carboxy-4-{4-[(2,4-diamino-5-c...)copy SMILEScopy InChI
Affinity DataKi:  0nMAssay Description:Compound was evaluated for the inhibition of Dihydrofolate reductase at concentration ranged from 0.15-0.50 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542P85PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50068811(CHEMBL149218 | N-(4-Carboxy-4-{4-[(2,4-diamino-5-m...)copy SMILEScopy InChI
Affinity DataKi:  0nMAssay Description:Compound was evaluated for the inhibition of Dihydrofolate reductase at concentration ranged from 0.15-0.50 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542P85PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50068809(CHEMBL150607 | N-(4-Carboxy-4-{4-[(2,4-diamino-5-m...)copy SMILEScopy InChI
Affinity DataKi:  0nMAssay Description:Compound was evaluated for the inhibition of Dihydrofolate reductase at concentration ranged from 0.15-0.50 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542P85PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50068808(CHEMBL297088 | N-(4-Carboxy-4-{4-[(2,4-diamino-qui...)copy SMILEScopy InChI
Affinity DataKi:  0.0000140nMAssay Description:Inhibitory activity against human recombinant Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V987CBPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50111552(CHEMBL297558 | N-(4-Carboxy-4-{4-[2-(6,8-diamino-n...)copy SMILEScopy InChI
Affinity DataKi:  0.000210nMAssay Description:Inhibitory activity against human recombinant Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V987CBPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50111550(CHEMBL296545 | N-(4-Carboxy-4-{4-[(6,8-diamino-qui...)copy SMILEScopy InChI
Affinity DataKi:  0.000330nMAssay Description:Inhibitory activity against human recombinant Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V987CBPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50111549(CHEMBL47689 | N-(4-Carboxy-4-{4-[2-(6,8-diamino-qu...)copy SMILEScopy InChI
Affinity DataKi:  0.000350nMAssay Description:Inhibitory activity against human recombinant Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V987CBPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50111548(CHEMBL47919 | N-(4-Carboxy-4-{4-[1-(6,8-diamino-qu...)copy SMILEScopy InChI
Affinity DataKi:  0.000600nMAssay Description:Inhibitory activity against human recombinant Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V987CBPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50111551(CHEMBL295859 | N-(4-Carboxy-4-{4-[1-(6,8-diamino-q...)copy SMILEScopy InChI
Affinity DataKi:  0.000620nMAssay Description:Inhibitory activity against human recombinant Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V987CBPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | AMINOPTE...)copy SMILEScopy InChI
Affinity DataKi:  0.00400nMAssay Description:Compound was evaluated for the inhibition of Dihydrofolate reductase at concentration ranged from 0.15-0.50 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542P85PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataKi:  0.00500nMAssay Description:Compound was evaluated for the inhibition of Dihydrofolate reductase at concentration ranged from 0.15-0.50 uMMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50158569(2-S-[5-[2,4-diaminopteridin-6-yl)methyamino]-2,3-d...)copy SMILEScopy InChI
Affinity DataKi:  0.0340nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ873FPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50158570(2-R,S-[5-[(2,4-diaminopteridin-6-yl)methylamino]-2...)copy SMILEScopy InChI
Affinity DataKi:  0.0770nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ873FPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50158571(2-S-[5-[N-(2,4--diaminopteridin-6-yl)methyl)-N-met...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ873FPubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50011885(5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-am...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RR1ZTRPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50158569(2-S-[5-[2,4-diaminopteridin-6-yl)methyamino]-2,3-d...)copy SMILEScopy InChI
Affinity DataKi:  280nMAssay Description:Inhibition of RFC-mediated [3H]MTX influx into human CCRF-CEM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ873FPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50158570(2-R,S-[5-[(2,4-diaminopteridin-6-yl)methylamino]-2...)copy SMILEScopy InChI
Affinity DataKi:  530nMAssay Description:Inhibition of RFC-mediated [3H]MTX influx into human CCRF-CEM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ873FPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50158571(2-S-[5-[N-(2,4--diaminopteridin-6-yl)methyl)-N-met...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of RFC-mediated [3H]MTX influx into human CCRF-CEM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ873FPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50039121((S)-2-{4-[(2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexa...)copy SMILEScopy InChI
Affinity DataKi:  2.37E+3nMAssay Description:Tested for the inhibition of [14C]-DDATHF influx in CCRF-CEM cells of human leukemic lymphoblastMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q240W0PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | AMINOPTE...)copy SMILEScopy InChI
Affinity DataKi:  1.76E+4nMAssay Description:Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RR1ZTRPubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50011886(5-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...)copy SMILEScopy InChI
Affinity DataKi:  2.04E+4nMAssay Description:Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RR1ZTRPubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataKi:  1.66E+5nMAssay Description:Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RR1ZTRPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011320(CHEMBL18155 | N-(4-Carboxy-4-{4-[(2,4-diamino-pter...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Tested in vitro for inhibitory concentration against CCRF-CEM human Leukemic lymphoblast by using DHFR as primary targetMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in humanMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85PXPubMedDrugBank
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50016460((S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-prop...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Tested in vitro for inhibitory concentration against CCRF-CEM human Leukemic lymphoblast by using DHFR as primary targetMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q240W0PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85PXPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031871(5-Chloro-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of Dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50031871(5-Chloro-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50035481(5-Chloro-N*6*-(3,4,5-trimethoxy-benzyl)-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031865(5-Chloro-6-{[methyl-(3,4,5-trimethoxy-phenyl)-amin...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of Dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50035481(5-Chloro-N*6*-(3,4,5-trimethoxy-benzyl)-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of Dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50039117(CHEMBL309160 | N-(4-Carboxy-4-{3,5-dichloro-4-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Tested for inhibitory concentration against human dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q240W0PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85PXPubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85PXPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50039119(CHEMBL44919 | N-(5-Carboxy-5-{4-[(2,4-diamino-pter...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:rested for inhibitory concentration against human dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q240W0PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Tested for inhibitory concentration against human dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031865(5-Chloro-6-{[methyl-(3,4,5-trimethoxy-phenyl)-amin...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of Dihydrofolate reductase of Pneumocystis cariniiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Tested for inhibitory concentration against human dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q240W0PubMedDrugBank
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50031865(5-Chloro-6-{[methyl-(3,4,5-trimethoxy-phenyl)-amin...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011320(CHEMBL18155 | N-(4-Carboxy-4-{4-[(2,4-diamino-pter...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Tested for inhibitory concentration against human dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50039118(CHEMBL42819 | N-(3-Carboxy-3-{4-[(2,4-diamino-pter...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Tested for inhibitory concentration against human dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q240W0PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | AMINOPTE...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Tested for inhibitory concentration against human dihydrofolate reductase(DHFR)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q240W0PubMed
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