Compile Data Set for Download or QSAR
Found 95 with Last Name = 'beierlein' and Initial = 'jm'
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26519(5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylp...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26521(6-ethyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-y...)copy SMILEScopy InChI
Affinity DataKi:  320nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329612(6-ethyl-5-(3-(5-methoxybiphenyl-3-yl)prop-1-ynyl)p...)copy SMILEScopy InChI
Affinity DataKi:  330nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26518(5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-methyl...)copy SMILEScopy InChI
Affinity DataKi:  360nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329609(5-(3-(biphenyl-3-yl)prop-1-ynyl)-6-ethylpyrimidine...)copy SMILEScopy InChI
Affinity DataKi:  370nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329610(6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)p...)copy SMILEScopy InChI
Affinity DataKi:  1.21E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM18490(6-methyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-...)copy SMILEScopy InChI
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329611(6-ethyl-5-(3-(4-methoxybiphenyl-2-yl)prop-1-ynyl)p...)copy SMILEScopy InChI
Affinity DataKi:  2.59E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM25818(5-[3-(3-methoxy-5-phenylphenyl)but-1-yn-1-yl]-6-me...)copy SMILEScopy InChI
Affinity DataKi:  2.66E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50298803((+/-)-6-methyl-5-(3-(3,4,5-trimethoxyphenyl)pent-1...)copy SMILEScopy InChI
Affinity DataKi:  3.37E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329608(6-methyl-5-(3-methyl-3-(3,4,5-trimethoxyphenyl)but...)copy SMILEScopy InChI
Affinity DataKi:  4.28E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM18494(3-(2,4-diamino-6-methylpyrimidin-5-yl)-1-(3,4,5-tr...)copy SMILEScopy InChI
Affinity DataKi:  4.89E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329613(5-(3-(2,5-dimethoxybiphenyl-4-yl)but-1-ynyl)-6-met...)copy SMILEScopy InChI
Affinity DataKi:  5.16E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM25822(5-[3-(3-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-me...)copy SMILEScopy InChI
Affinity DataKi:  5.83E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM18496(5-[3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-yn-1...)copy SMILEScopy InChI
Affinity DataKi:  9.81E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM18492(6-methyl-5-[3-(3,4,5-trimethoxyphenyl)but-1-yn-1-y...)copy SMILEScopy InChI
Affinity DataKi:  1.02E+4nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329607(5-(3-(3-methoxybiphenyl-4-yl)but-1-ynyl)-6-methylp...)copy SMILEScopy InChI
Affinity DataKi:  1.17E+4nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataKi:  2.41E+4nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Dartmouth College

LigandPNGBDBM18497(6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)but-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0KKQPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Dartmouth College

LigandPNGBDBM18498(6-methyl-5-[(3S)-3-(3,4,5-trimethoxyphenyl)but-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0KKQPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Dartmouth College

LigandPNGBDBM18497(6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)but-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 38nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0KKQPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM26521(6-ethyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Dartmouth College

LigandPNGBDBM18492(6-methyl-5-[3-(3,4,5-trimethoxyphenyl)but-1-yn-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0KKQPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM26522(5-[3-(2,3-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylp...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Dartmouth College

LigandPNGBDBM18492(6-methyl-5-[3-(3,4,5-trimethoxyphenyl)but-1-yn-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 169nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0KKQPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM26523(6-ethyl-5-(3-phenylprop-1-yn-1-yl)pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM18490(6-methyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Dartmouth College

LigandPNGBDBM18496(5-[3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-yn-1...)copy SMILEScopy InChI
Affinity DataIC50: 550nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0KKQPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Dartmouth College

LigandPNGBDBM18490(6-methyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-...)copy SMILEScopy InChI
Affinity DataIC50: 880nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0KKQPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26519(5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylp...)copy SMILEScopy InChI
Affinity DataIC50: 890nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26519(5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylp...)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26521(6-ethyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 942nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26521(6-ethyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 942nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329612(6-ethyl-5-(3-(5-methoxybiphenyl-3-yl)prop-1-ynyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 973nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26518(5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50329609(5-(3-(biphenyl-3-yl)prop-1-ynyl)-6-ethylpyrimidine...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of wild type Bacillus anthracis recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RSRPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM18495(5-[3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-yn-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+3nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM26520(5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM18496(5-[3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-yn-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+3nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM26519(5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylp...)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+3nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26518(5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM26518(5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM18492(6-methyl-5-[3-(3,4,5-trimethoxyphenyl)but-1-yn-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+3nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM18489(5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-yl]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University of Connecticut

LigandPNGBDBM18491(5-[3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26517(5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Dartmouth College

LigandPNGBDBM18498(6-methyl-5-[(3S)-3-(3,4,5-trimethoxyphenyl)but-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.91E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0KKQPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM18489(5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-yl]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Dartmouth College

LigandPNGBDBM18491(5-[3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0KKQPubMed
TargetDihydrofolate reductase(Bacillus anthracis)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM26523(6-ethyl-5-(3-phenylprop-1-yn-1-yl)pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH oxidation at an absorbance of 340 nm over several minutes. All...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P8496HPubMed
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