Compile Data Set for Download or QSAR
Found 42 with Last Name = 'shoemaker' and Initial = 'kr'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50039664(CHEMBL91890 | N-Biphenyl-4-yl-N-[(carbamoylmethyl-...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50039665(CHEMBL90649 | CHIR-4531 | N-Benzo[1,3]dioxol-5-ylm...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from rat brain membrane using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50039661(CHEMBL327549 | CHIR-4537 | N-({Carbamoylmethyl-[2-...)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from rat brain membrane using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50039663(CHEMBL89378 | CHIR-4534 | N-({Carbamoylmethyl-[2-(...)copy SMILEScopy InChI
Affinity DataKi:  46nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from rat brain membrane using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50029051((-)-arterenol | (-)-noradrenaline | (-)-norepineph...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+4nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331592(3-(6-(6-methoxypyridin-3-ylamino)-2-morpholinopyri...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331592(3-(6-(6-methoxypyridin-3-ylamino)-2-morpholinopyri...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331577(3-(6-(1H-indazol-5-ylamino)-2-morpholinopyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331577(3-(6-(1H-indazol-5-ylamino)-2-morpholinopyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331593(3-(2-morpholino-6-(pyridin-3-yloxy)pyrimidin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331591(3-(2-morpholino-6-(pyridin-3-ylamino)pyrimidin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331590(3-(6-(4-methoxyphenylamino)-2-morpholinopyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331592(3-(6-(6-methoxypyridin-3-ylamino)-2-morpholinopyri...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331577(3-(6-(1H-indazol-5-ylamino)-2-morpholinopyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331587(3-(2-morpholinopyrimidin-4-yl)phenol | CHEMBL12886...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331595(3-(6-(4-hydroxycyclohexylamino)-2-morpholinopyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331597(3-(2,6-dimorpholinopyrimidin-4-yl)phenol | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331596(1-(4-(6-(3-hydroxyphenyl)-2-morpholinopyrimidin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331577(3-(6-(1H-indazol-5-ylamino)-2-morpholinopyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331578(2-(6-(1H-indazol-5-ylamino)-2-morpholinopyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331588(3-(6-(methylamino)-2-morpholinopyrimidin-4-yl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331589(3-(2-morpholino-6-(phenylamino)pyrimidin-4-yl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331594(3-(2-morpholino-6-(pyridin-3-ylmethylamino)pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331598(3-(6-(1H-indazol-5-ylamino)-2-thiomorpholinopyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331579(4-(6-(1H-indazol-5-ylamino)-2-morpholinopyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331599(3-[6-(1H-Indazol-5-ylamino)-2-(1-oxo-1lambda4-thio...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331580(CHEMBL1290175 | N-(2-morpholino-6-phenylpyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331581(CHEMBL1290176 | N-(6-(3-fluorophenyl)-2-morpholino...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331602(3-(6-(1H-indazol-5-ylamino)-2-((2S,6R)-2,6-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331586(2-(3-(6-(1H-indazol-5-ylamino)-2-morpholinopyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331582(CHEMBL1290286 | N-(6-(3-chlorophenyl)-2-morpholino...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331584(3-(6-(1H-indazol-5-ylamino)-2-morpholinopyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331583(CHEMBL1290287 | N-(6-(3-methoxyphenyl)-2-morpholin...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331601(3-(6-(1H-indazol-5-ylamino)-2-(2-methoxyethylamino...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331600(3-(6-(1H-indazol-5-ylamino)-2-(piperazin-1-yl)pyri...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331585(CHEMBL1290403 | methyl 3-(6-(1H-indazol-5-ylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50331577(3-(6-(1H-indazol-5-ylamino)-2-morpholinopyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B6CPubMed