Found 165 with Last Name = 'd''hooghe' and Initial = 'm' TargetHistone deacetylase 3(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(acetyl)-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC10 (1 to 631 residues) expressed in baculovirus expression system in Sf9 cells RHKAcKAc after 2 hrs by ...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Inhibition of full length human HDAC8 expressed in an E. coli expression system using AMC-labeled RHKAcKAc as substrate after 2 hrs by fluorescence a...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(acetyl)-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus expression system in Sf9 cells using AMC-labeled RHKKAc as subst...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human HDAC3 using Boc-Lys (Ac)-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human HDAC6 using RHKKAc as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(acetyl)-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Zea mays)
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(acetyl)-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(acetyl)-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC7 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys (Ac)-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(acetyl)-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
TargetHistone deacetylase 1(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys (Ac)-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC6 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
In DepthDetails
3D Structure (crystal)TargetHistone deacetylase 2(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human HDAC2 using Boc-Lys (Ac)-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus expression system using AMC-labeled RHKKAc as substrat...More data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(acetyl)-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
In DepthDetails
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))TBA
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of human HDAC6 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus expression system after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of C-terminal GST-tagged full length human HDAC1 expressed in baculovirus expression system in Sf9 cells using AMC-labeled RHKKAc as subst...More data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
