TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 catalytic domain (970 to 2527 residues) expressed in baculovirus expression system using LRRKtide as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0320nMAssay Description:Inhibition of recombinant human full length His-tagged JNK1 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0590nMAssay Description:Inhibition of recombinant human full length His-tagged JNK2 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Displacement of [125I]nonpeptide ligand (compound 7) from purified human recombinant alphaV-beta3More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Displacement of [125I]nonpeptide ligand (compound 7) from purified human recombinant alphaV-beta3More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]echistatin from human recombinant alpha-v beta-3 receptorMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 0.104nMAssay Description:Inhibition of recombinant human full length GST-tagged DYRK3 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.107nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged JNK3 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetTestis-specific serine/threonine-protein kinase 1(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 0.217nMAssay Description:Inhibition of recombinant human full length His-tagged TSSK1 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Celgene Corporation
Curated by ChEMBL
Celgene Corporation
Curated by ChEMBL
Affinity DataIC50: 0.261nMAssay Description:Inhibition of recombinant human GST-tagged CLK2 catalytic domain (137 to 498 residues) expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]echistatin from human recombinant alpha-v beta-3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of rate of ADP-stimulated gel-filtered human platelet aggregation mediated by integrin alphaIIb beta-3 in PLAGGIN assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]echistatin from human recombinant alpha-v beta-3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Displacement of [125I]nonpeptide ligand (compound 7) from purified human recombinant alphaV-beta3More data for this Ligand-Target Pair
Affinity DataIC50: 0.567nMAssay Description:Inhibition of recombinant human GST-tagged LTK cytoplasmic domain (450 to 864 residues) expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]echistatin from human recombinant alpha-v beta-3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:Displacement of [125I]nonpeptide ligand (compound 7) from purified human recombinant alphaV-beta3More data for this Ligand-Target Pair
Affinity DataIC50: 0.940nMAssay Description:Displacement of a non-peptide radioligand from human recombinant alphaV-beta3 integrinMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of rate of ADP-stimulated gel-filtered human platelet aggregation mediated by integrin alphaIIb beta-3 in PLAGGIN assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of rate of ADP-stimulated gel-filtered human platelet aggregation mediated by integrin alphaIIb beta-3 in PLAGGIN assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]echistatin from human recombinant alpha-v beta-3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of rate of ADP-stimulated gel-filtered human platelet aggregation mediated by integrin alphaIIb beta-3 in PLAGGIN assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Kinase Tracer 236 binding to recombinant human full-length GST-tagged TTk expressed in baculovirus expression system measured after 1 h...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human full length recombinant GST-tagged TTK expressed in baculovirus by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair