TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKi: 410nMAssay Description:Irreversible inhibition of KDM5A ARID/PhD1 domain deletion mutant (1 to 739 residues) (unknown origin)More data for this Ligand-Target Pair
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PHKgamma2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of CAMK2BMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Inhibition of CDK2/cyclinAMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
TargetDeath-associated protein kinase 1(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human full-length recombinant N-terminal His-tagged BRD4 (2 to 1362 residues) expressed in Sf9 cells using histone H4 peptide containin...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
National Center for Advancing Translational Sciences
Curated by ChEMBL
National Center for Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair