Compile Data Set for Download or QSAR
Found 66 with Last Name = 'alberti' and Initial = 'mj'
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168577(4-(1-Cyclopropyl-1H-imidazo[4,5-c]pyridin-2-yl)-fu...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168587(4-(1-Cyclohexyl-1H-imidazo[4,5-c]pyridin-2-yl)-fur...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168581(4-(1-Phenyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168578(4-[1-(1-Amino-butyl)-1H-imidazo[4,5-c]pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168594(2-(4-Amino-furazan-3-yl)-1-ethyl-1H-benzoimidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168601(4-(1-Piperidin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168576(3-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyrazin-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169697(CHEMBL182254 | [3-Chloro-4-(3-fluoro-benzyloxy)-ph...)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 7.5Assay Description:Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BDMPubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168595(4-(1-Ethyl-5-fluoro-1H-benzoimidazol-2-yl)-furazan...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169696((4-Benzyloxy-3-chloro-phenyl)-(1,3,8a,9-tetraaza-f...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.5Assay Description:Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BDMPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275583(7-ethoxy-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168586(4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-5-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169697(CHEMBL182254 | [3-Chloro-4-(3-fluoro-benzyloxy)-ph...)copy SMILEScopy InChI
Affinity DataIC50: 63nMpH: 7.5Assay Description:Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BDMPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275614(2-(4-fluorophenyl)-3-(pyridin-4-yl)-7-(2,2,2-trifl...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168589(3-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275499(2-(4-fluorophenyl)-3-(4-pyridinyl)pyrazolo-[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168582(4-(1-Methyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan...)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275579(2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168588(4-(1-Ethyl-1H-benzoimidazol-2-yl)-furazan-3-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275581(7-chloro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275551(2-(4-fluorophenyl)-7-methyl-3-(pyridin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275580(6-chloro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275547(6-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275549(2-(4-fluorophenyl)-5-methyl-3-(pyridin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275582(7-(cyclopentyloxy)-2-(4-fluorophenyl)-3-(pyridin-4...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169701((3-Chloro-4-fluoro-phenyl)-(1,3,8a,9-tetraaza-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 200nMpH: 7.5Assay Description:Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BDMPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275552(2-(4-fluorophenyl)-3-(pyridin-4-yl)-6-(trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169696((4-Benzyloxy-3-chloro-phenyl)-(1,3,8a,9-tetraaza-f...)copy SMILEScopy InChI
Affinity DataIC50: 200nMpH: 7.5Assay Description:Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BDMPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275500(4-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168593(2-(4-Amino-furazan-3-yl)-3-ethyl-3H-benzoimidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 258nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275548(2-(4-fluorophenyl)-4-methyl-3-(pyridin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168598(CHEMBL185731 | [2-(4-Amino-furazan-3-yl)-1-ethyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 974nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168592(4-(1-Ethyl-5-methoxy-1H-benzoimidazol-2-yl)-furaza...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168599(4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168584(4-(3-Ethyl-3H-imidazo[4,5-c]pyridin-2-yl)-furazan-...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169699((2-Benzyl-1H-benzoimidazol-5-yl)-(1,3,8a,9-tetraaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+3nMpH: 7.5Assay Description:Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BDMPubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168600(4-(1H-Imidazo[4,5-c]pyridin-2-yl)-furazan-3-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168591(4-(1-Ethyl-6-fluoro-1H-benzoimidazol-2-yl)-furazan...)copy SMILEScopy InChI
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275499(2-(4-fluorophenyl)-3-(4-pyridinyl)pyrazolo-[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168583(1-[2-(4-Amino-furazan-3-yl)-1-ethyl-1H-benzoimidaz...)copy SMILEScopy InChI
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50169699((2-Benzyl-1H-benzoimidazol-5-yl)-(1,3,8a,9-tetraaz...)copy SMILEScopy InChI
Affinity DataIC50: 5.01E+3nMpH: 7.5Assay Description:Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84BDMPubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168585(CHEMBL362494 | N-[4-(1-Ethyl-1H-imidazo[4,5-c]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275499(2-(4-fluorophenyl)-3-(4-pyridinyl)pyrazolo-[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of c-Raf (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50275499(2-(4-fluorophenyl)-3-(4-pyridinyl)pyrazolo-[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NM9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168579(5-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168574(1-Ethyl-2-furan-3-yl-1H-imidazo[4,5-c]pyridine | C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168575(1-Ethyl-2-pyridin-3-yl-1H-imidazo[4,5-c]pyridine |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50168580(2-(1,2-Dihydro-pyridin-2-yl)-1-ethyl-1H-imidazo[4,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
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