Compile Data Set for Download or QSAR
Found 343 with Last Name = 'cornelius' and Initial = 'p'
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123058(2-(3,5-dichloro-4-(4-hydroxy-3-(piperidin-1-ylsulf...)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123046(2-[4-(4-Hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123044(5-(2,6-dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-tri...)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123044(5-(2,6-dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-tri...)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123045(CHEMBL413699 | N-Cyclohexyl-5-[2,6-dichloro-4-(3,5...)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123054(5-(2,6-dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-tri...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123064(2-(3-chloro-4-(4-hydroxy-3-(piperidin-1-ylsulfonyl...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123063(2-{3,5-Dichloro-4-[4-hydroxy-3-(indole-1-sulfonyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.230nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123052(2-[4-(3-{8-azaspiro[bicyclo[3.2.1]octane-3,2'-oxol...)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Inhibitory activity against [125I]T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123061(2-[4-(3-{8-azaspiro[bicyclo[3.2.1]octane-3,2'-[1,3...)copy SMILEScopy InChI
Affinity DataKi:  0.310nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123059(2-{4-[3-(2-Aza-bicyclo[2.2.1]heptane-2-carbonyl)-4...)copy SMILEScopy InChI
Affinity DataKi:  0.370nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123059(2-{4-[3-(2-Aza-bicyclo[2.2.1]heptane-2-carbonyl)-4...)copy SMILEScopy InChI
Affinity DataKi:  0.370nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123057(CHEMBL124039 | N-Cyclobutyl-5-[2,6-dichloro-4-(3,5...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123056(2-(4-(4-hydroxy-3-(piperidin-1-ylsulfonyl)phenoxy)...)copy SMILEScopy InChI
Affinity DataKi:  0.460nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123062(CHEMBL340158 | N-Cyclohexyl-5-[2,6-dichloro-4-(3,5...)copy SMILEScopy InChI
Affinity DataKi:  0.460nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123059(2-{4-[3-(2-Aza-bicyclo[2.2.1]heptane-2-carbonyl)-4...)copy SMILEScopy InChI
Affinity DataKi:  0.590nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304826((S)-7-(2-chlorophenoxy)-2-((R)-2-methylpiperazin-1...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]5HT from human 5HT2C receptor expressed in mouse 3T3 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123049(2-(3,5-dichloro-4-(4-hydroxy-3-(piperidine-1-carbo...)copy SMILEScopy InChI
Affinity DataKi:  0.630nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123050(CHEMBL124318 | N-Cyclobutyl-5-[2,6-dichloro-4-(3,5...)copy SMILEScopy InChI
Affinity DataKi:  0.640nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304805((S)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assay relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304802((S)-8-(2-chlorophenoxy)-2-(piperazin-1-yl)-5,6,7,8...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]DOI from rat 5HT2A receptor expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50380913(CHEMBL2016732)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154J34PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123055(2-(3,5-dichloro-4-(4-hydroxy-3-(morpholine-4-carbo...)copy SMILEScopy InChI
Affinity DataKi:  0.720nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50380915(CHEMBL2016682)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154J34PubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50380923(CHEMBL2016740)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154J34PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50314613((S)-N-(4-(4,4-dimethylcyclohexyloxy)-5-fluoro-2-me...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94QJPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304804(7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dihydro...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assay relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304805((S)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [125I]DOI from rat 5HT2A receptor expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50380922(CHEMBL2016739)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154J34PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304808(4-chloro-2-(piperazin-1-yl)thieno[2,3-d]pyrimidine...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assay relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50123737(3-{2-[6-(2-tert-Butoxy-ethoxy)-pyridin-3-yl]-3H-im...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154J34PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304802((S)-8-(2-chlorophenoxy)-2-(piperazin-1-yl)-5,6,7,8...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assay relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304807((S)-7-(5-fluoro-2-methylbenzyloxy)-2-((R)-2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assay relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50304300(CHEMBL595573 | trans-N-[1-(2-fluorophenyl)-3-pyraz...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154J34PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50314616((S)-N-(4-(cyclohexylmethoxy)-5-fluoro-2-methoxyben...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94QJPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50314614((S)-N-(4-(4,4-dimethylcyclohexyloxy)-2,5-difluorob...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94QJPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123060(2-{3-Chloro-4-[4-hydroxy-3-(piperidine-1-carbonyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123053(2-[3,5-Dimethyl-4-(3-methyl-4-methylsulfanyl-pheno...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304803((R)-8-(2-chlorophenoxy)-2-(piperazin-1-yl)-5,6,7,8...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Displacement of [125I]DOI from rat 5HT2A receptor expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50380920(CHEMBL2016737)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154J34PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304827((S)-7-(3-fluorophenoxy)-2-(piperazin-1-yl)-6,7-dih...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Displacement of [3H]5HT from human 5HT2C receptor expressed in mouse 3T3 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50440252(CHEMBL2426686)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HP5PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304804(7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dihydro...)copy SMILEScopy InChI
Affinity DataKi:  3.80nMAssay Description:Displacement of [125I]DOI from rat 5HT2A receptor expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50314618(CHEMBL1090397 | N-((4'-chloro-3-fluorobiphenyl-4-y...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94QJPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304809(4-(3-chlorobenzyloxy)-2-(piperazin-1-yl)thieno[2,3...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Agonist activity against human 5HT2C receptor by FLIPR assay relative to 5HTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50440255(CHEMBL2426683)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7HP5PubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50304807((S)-7-(5-fluoro-2-methylbenzyloxy)-2-((R)-2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:Displacement of [125I]DOI from rat 5HT2A receptor expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H5MPubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50314623((S)-N-(4-cyclohexylbenzyl)pyrrolidine-2-carboxamid...)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94QJPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50380925(CHEMBL2016742)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154J34PubMed
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