Compile Data Set for Download or QSAR
Found 213 with Last Name = 'bahekar' and Initial = 'r'
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50420657(CHEMBL2086613)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM124215(({7-[2-(1H-1,2,3-benzotriazol-1-yl)-2-({6-bromo-7-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HGZPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMedDrugBank
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50420653(CHEMBL2086614)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM124216(({7-[2-({7-[(aminosulfinyl)difluoromethyl]-6-bromo...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HGZPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM124221(({2-[2-({7-[(aminosulfinyl)difluoromethyl]-6-bromo...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HGZPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421200(CHEMBL2087289)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in baculovirus infected Sf9 cells after overnight incubation by scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70H37PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421197(CHEMBL2087286)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in baculovirus infected Sf9 cells after overnight incubation by scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70H37PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM124220(({2-[2-(1H-1,2,3-benzotriazol-1-yl)-2-({6-bromo-7-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HGZPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM50362181(({7-[2-(1H-1,2,3-benzotriazol-1-yl)-2-({6-bromo-7-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HGZPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM50362181(({7-[2-(1H-1,2,3-benzotriazol-1-yl)-2-({6-bromo-7-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523669(CHEMBL4535169)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM124217(({7-[2-({7-[(aminosulfinyl)difluoromethyl]-6-bromo...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HGZPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523672(CHEMBL4440218)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM11113(6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50004098(CHEMBL3236121)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G7FPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM50362195(CHEMBL1938828)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50420651(CHEMBL2086611)copy SMILEScopy InChI
Affinity DataIC50: 10.3nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM50362196(CHEMBL1938829)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523673(CHEMBL4589873)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523670(CHEMBL4467333)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50420654(CHEMBL2086615)copy SMILEScopy InChI
Affinity DataIC50: 11.6nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50420652(CHEMBL2086612)copy SMILEScopy InChI
Affinity DataIC50: 13.2nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50420655(CHEMBL2086616)copy SMILEScopy InChI
Affinity DataIC50: 14.3nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM50362191(CHEMBL1938824)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM50362192(CHEMBL1938825)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM11162((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523674(CHEMBL4536349)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50420640(CHEMBL2086600)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50004103(CHEMBL3236126)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G7FPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM124211(({7-[2-({4-[(aminosulfinyl)difluoromethyl]-3-bromo...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HGZPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421198(CHEMBL2087287)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in baculovirus infected Sf9 cells after 16-18 hrs by beta countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70H37PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM124209(({7-[2-(1H-1,2,3-benzotriazol-1-yl)-2-({3-bromo-4-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HGZPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523665(CHEMBL4542493)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421198(CHEMBL2087287)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in baculovirus infected Sf9 cells after overnight incubation by scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70H37PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM124218(({2-[2-(1H-1,2,3-benzotriazol-1-yl)-2-({3-bromo-4-...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HGZPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM124219(({2-[2-({4-[(aminosulfinyl)difluoromethyl]-3-bromo...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HGZPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50420639(CHEMBL2086599)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50420633(CHEMBL2086592)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2C77PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523666(CHEMBL4462149)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523671(CHEMBL4563971)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Zydus Research Centre

LigandPNGBDBM50362186(CHEMBL1938819)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of PTP1B assessed as para-nitrophenyl phosphate catalyzed hydrolysis of para-nitrophenol by p-NPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2X05PubMed
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