BindingDB PrimarySearch

Found 40 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50403068'

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 1nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 1.20nMAssay Description:Inhibition of PI3K delta (unknown origin) using phosphatidyl inositol as substrate measured after 60 mins in presence of ATP by Kinase-Glo Plus reage...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2MC93GXPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 1.60nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using Biotin-S11S12 as substrate after 120 mins in presence of ATP by ADPGlo luminescence assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q21N83S2PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 60 mins using fluorescein-labeled kinase tracer by HTRF assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25M684RPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WW7KVJPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate in presence of ATP measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q29P35GSPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2736V7KPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.10nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2Z89DR9PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.5nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN99PGPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by Selectscreen kinase assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q27M0CRDPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of recombinant human His-tagged PI3Kdelta expressed in baculovirus expression system using PIP2:PS as substrate incubated for 1 hr by invi...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2MG7T7RPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of PI3Kdelta in basophil derived from B-cell malignant patientMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q25D8W6SPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of human recombinant PI3K-deltaMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q29S1TN5PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2Z89G25PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.5nMAssay Description:Inhibition of human full length His-tagged PI3Kdelta expressed in baculovirus expression systemMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2FF3VTCPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.70nMAssay Description:Inhibition of PI3K p110delta (unknown origin) using lipid substrate after 40 mins by kinase-Glo assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2Z89G25PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 2.70nMAssay Description:Inhibition of PI3Kdelta (unknown origin) assessed as inhibition of AKT phosphorylation by cell-based HTRF assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2H41T39PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 3.10nMAssay Description:Inhibition of PI3K delta (unknown origin) using lipid substrate measured after 40 mins in presence of ATP by Kinase-Glo plus reagent based luminescen...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2833W8MPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 4nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in antihuman IgM-stimulated AKT phosphorylation at Ser473 residue preincubated for...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q20R9SR0PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 4.30nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2FF3VTCPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 4.70nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2MG7T7RPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 4.90nMAssay Description:1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS.2. Compound was formulated in 100% DMSO in a concentratio...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2RJ4MM0US Patent PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 5.90nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr in p...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2BR8VRJPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 6nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2QC0752PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 6.10nMAssay Description:Inhibition of PI3Kdelta in B-cells by proliferation assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2SN0B47PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 7nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q20869DRPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 9nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2SN0B47PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 9nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 9nMAssay Description:Compounds of the invention were tested for inhibitory activity and potency against PI3Kδ.More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2RV0M9JUS Patent PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 9nMAssay Description:Biochemical assay using PI3K delta.More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2736PJJUS Patent PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 10nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using biotin-PIP3 as substrate preincubated for 15 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q27H1P12PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

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BindingDB Entry DOI: 10.7270/Q27H1P12PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 19nMAssay Description:Inhibition of PIK3CD (unknown origin)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2ZG6WHWPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 24nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by biochemical Alphascreen assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2H41T39PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 25nMAssay Description:Inhibition of human PI3KCdelta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2M61MWRPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 31nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2H13624PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 49nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2H13624PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

IC50: 831nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA

BDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI

EC50: 8nMMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN99PGPubMed PDB

3D Structure (crystal)

Targets 1 ▿
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 40
Publications 22 ▿
- Bioorg Med Chem 26: 2028-2040 (2018) 2
- J Med Chem 55: 8559-81 (2012) 2
- Eur J Med Chem 125: 1156-1171 (2017) 2
- J Med Chem 62: 10402-10422 (2019) 2
- Bioorg Med Chem Lett 29: 1313-1319 (2019) 2
- Bioorg Med Chem Lett 25: 1104-9 (2015) 2
- US Patent USRE44599 (2013) 1
- Bioorg Med Chem 27: (2019) 1
- J Med Chem 62: 10005-10025 (2019) 1
- Eur J Med Chem 156: 831-846 (2018) 1
- Bioorg Med Chem Lett 28: 1005-1010 (2018) 1
- J Med Chem 56: 1922-39 (2013) 1
- J Med Chem 62: 4783-4814 (2019) 1
- US Patent US8586597 (2013) 1
- J Med Chem 62: 4936-4948 (2019) 1
- Eur J Med Chem 151: 9-17 (2018) 1
- Bioorg Med Chem Lett 27: 2849-2853 (2017) 1
- Bioorg Med Chem 27: (2019) 1
- ACS Med Chem Lett 6: 3-6 (2015) 1
- J Med Chem 60: 5193-5208 (2017) 1
- US Patent US9745321 (2017) 1
- Eur J Med Chem 163: 413-427 (2019) 1
Institutions 18 ▿
- [Xi'an Jiaotong University] 4
- [University of Nottingham , Zydus Research Centre, Amgen Inc., Shanghai Institute of Materia Medica (SIMM), ICOS Corporation, Bristol-Myers Squibb Company, Amgen Inc.] 2
- [University of Nottingham , Zydus Research Centre, Amgen Inc., Shanghai Institute of Materia Medica (SIMM), ICOS Corporation, Bristol-Myers Squibb Company, Amgen Inc.] 2
- [University of Nottingham , Zydus Research Centre, Amgen Inc., Shanghai Institute of Materia Medica (SIMM), ICOS Corporation, Bristol-Myers Squibb Company, Amgen Inc.] 2
- [University of Nottingham , Zydus Research Centre, Amgen Inc., Shanghai Institute of Materia Medica (SIMM), ICOS Corporation, Bristol-Myers Squibb Company, Amgen Inc.] 2
- [University of Nottingham , Zydus Research Centre, Amgen Inc., Shanghai Institute of Materia Medica (SIMM), ICOS Corporation, Bristol-Myers Squibb Company, Amgen Inc.] 2
- [University of Nottingham , Zydus Research Centre, Amgen Inc., Shanghai Institute of Materia Medica (SIMM), ICOS Corporation, Bristol-Myers Squibb Company, Amgen Inc.] 2
- [University of Nottingham , Zydus Research Centre, Amgen Inc., Shanghai Institute of Materia Medica (SIMM), ICOS Corporation, Bristol-Myers Squibb Company, Amgen Inc.] 2
- [Chinese Academy of Sciences, Boston University, India Academy of Scientific & Innovative Research (AcSIR), China Pharmaceutical University, SHANGHAI YINGLI PHARMACEUTICAL CO., LTD, Monash University (Parkville Campus), Hutchison MediPharma Limited, Shandong University, AstraZeneca, The University of Arizona] 1
- [Chinese Academy of Sciences, Boston University, India Academy of Scientific & Innovative Research (AcSIR), China Pharmaceutical University, SHANGHAI YINGLI PHARMACEUTICAL CO., LTD, Monash University (Parkville Campus), Hutchison MediPharma Limited, Shandong University, AstraZeneca, The University of Arizona] 1
- [Chinese Academy of Sciences, Boston University, India Academy of Scientific & Innovative Research (AcSIR), China Pharmaceutical University, SHANGHAI YINGLI PHARMACEUTICAL CO., LTD, Monash University (Parkville Campus), Hutchison MediPharma Limited, Shandong University, AstraZeneca, The University of Arizona] 1
- [Chinese Academy of Sciences, Boston University, India Academy of Scientific & Innovative Research (AcSIR), China Pharmaceutical University, SHANGHAI YINGLI PHARMACEUTICAL CO., LTD, Monash University (Parkville Campus), Hutchison MediPharma Limited, Shandong University, AstraZeneca, The University of Arizona] 1
- [Chinese Academy of Sciences, Boston University, India Academy of Scientific & Innovative Research (AcSIR), China Pharmaceutical University, SHANGHAI YINGLI PHARMACEUTICAL CO., LTD, Monash University (Parkville Campus), Hutchison MediPharma Limited, Shandong University, AstraZeneca, The University of Arizona] 1
- [Chinese Academy of Sciences, Boston University, India Academy of Scientific & Innovative Research (AcSIR), China Pharmaceutical University, SHANGHAI YINGLI PHARMACEUTICAL CO., LTD, Monash University (Parkville Campus), Hutchison MediPharma Limited, Shandong University, AstraZeneca, The University of Arizona] 1
- [Chinese Academy of Sciences, Boston University, India Academy of Scientific & Innovative Research (AcSIR), China Pharmaceutical University, SHANGHAI YINGLI PHARMACEUTICAL CO., LTD, Monash University (Parkville Campus), Hutchison MediPharma Limited, Shandong University, AstraZeneca, The University of Arizona] 1
- [Chinese Academy of Sciences, Boston University, India Academy of Scientific & Innovative Research (AcSIR), China Pharmaceutical University, SHANGHAI YINGLI PHARMACEUTICAL CO., LTD, Monash University (Parkville Campus), Hutchison MediPharma Limited, Shandong University, AstraZeneca, The University of Arizona] 1
- [Chinese Academy of Sciences, Boston University, India Academy of Scientific & Innovative Research (AcSIR), China Pharmaceutical University, SHANGHAI YINGLI PHARMACEUTICAL CO., LTD, Monash University (Parkville Campus), Hutchison MediPharma Limited, Shandong University, AstraZeneca, The University of Arizona] 1
- [Chinese Academy of Sciences, Boston University, India Academy of Scientific & Innovative Research (AcSIR), China Pharmaceutical University, SHANGHAI YINGLI PHARMACEUTICAL CO., LTD, Monash University (Parkville Campus), Hutchison MediPharma Limited, Shandong University, AstraZeneca, The University of Arizona] 1
Affinity: 1 to 8.3E+2 nM▿
- IC50 39
- EC50 1
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 1