Found 371 with Last Name = 'stowe' and Initial = 'rl' TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 6nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 9nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 45nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 60nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 60nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 60nMpH: 8.0Assay Description:Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 70nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University
University of Florida College of Medicine; Northwest Agriculture and Forestry University
Affinity DataIC50: 70nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 8.0Assay Description:Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 120nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University
University of Florida College of Medicine; Northwest Agriculture and Forestry University
Affinity DataIC50: 120nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 130nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University
University of Florida College of Medicine; Northwest Agriculture and Forestry University
Affinity DataIC50: 150nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 150nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University
University of Florida College of Medicine; Northwest Agriculture and Forestry University
Affinity DataIC50: 190nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University
University of Florida College of Medicine; Northwest Agriculture and Forestry University
Affinity DataIC50: 190nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 220nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University
University of Florida College of Medicine; Northwest Agriculture and Forestry University
Affinity DataIC50: 220nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University
University of Florida College of Medicine; Northwest Agriculture and Forestry University
Affinity DataIC50: 230nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University
University of Florida College of Medicine; Northwest Agriculture and Forestry University
Affinity DataIC50: 320nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
Affinity DataIC50: 380nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
University of Florida Research Foundation, Inc.; The Scripps Research Institute
US Patent
