Compile Data Set for Download or QSAR
Found 710 with Last Name = 'mathieu' and Initial = 's'
LigandPNGBDBM50363990(CHEMBL1949915)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419769(CHEMBL1950034)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419754(CHEMBL1949910)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50347090(CHEMBL1796276)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419759(CHEMBL1949916)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419770(CHEMBL1950035)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50347087(CHEMBL1796273)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419761(CHEMBL1949919)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419773(CHEMBL1949917)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419760(CHEMBL1949918)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50097131(CHEMBL3580667)copy SMILES
Affinity DataKi:  2nMAssay Description:Inhibition of human PAK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1MN9PubMed
LigandPNGBDBM50419758(CHEMBL1949914)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50358203(CHEMBL1922093)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of PI3K subunit p110alpha assessed as formation of phosphatidylinositide-3-phosphate product formation after 30 mins by fluorescence polar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WMTPubMed
LigandPNGBDBM50419762(CHEMBL1949920)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50096231(CHEMBL3580975)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GWTPubMed
LigandPNGBDBM50363991(CHEMBL1796763)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419771(CHEMBL1950036)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50315914((3-(2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholin...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant mTOR assessed as reduction in GFP-4EBP1 phosphorylation after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM87FXPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50315915(5-(7-methyl-6-(3-(methylsulfonyl)phenyl)-4-morphol...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant mTOR assessed as reduction in GFP-4EBP1 phosphorylation after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM87FXPubMed
LigandPNGBDBM50419764(CHEMBL1949922)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50185825(CHEMBL3824224)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DQJPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50096231(CHEMBL3580975)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1MN9PubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50097144(CHEMBL3580963)copy SMILES
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant PAK4 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1MN9PubMed
LigandPNGBDBM50419766(CHEMBL1949924)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419765(CHEMBL1949923)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419757(CHEMBL1949913)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50096231(CHEMBL3580975)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GWTPubMed
LigandPNGBDBM50419772(CHEMBL1950037)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50315911(5-(6-(3-(methylsulfonyl)phenyl)-4-morpholinothieno...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant mTOR assessed as reduction in GFP-4EBP1 phosphorylation after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM87FXPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50185823(CHEMBL3823612)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DQJPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50097128(CHEMBL3580976)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1MN9PubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50097135(CHEMBL3580974)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1MN9PubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50097128(CHEMBL3580976)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:Inhibition of aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1MN9PubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50185827(CHEMBL3823523)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DQJPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50358206(CHEMBL1922091)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 measured after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WMTPubMed
LigandPNGBDBM50419757(CHEMBL1949913)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Apparent binding affinity to PI3Kbeta using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50419756(CHEMBL1949912)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50315913((3-(2-(2-aminopyrimidin-5-yl)-4-morpholinothieno[3...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant mTOR assessed as reduction in GFP-4EBP1 phosphorylation after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM87FXPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50315908(CHEMBL1090598 | N-((2-(2-aminopyrimidin-5-yl)-4-mo...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant mTOR assessed as reduction in GFP-4EBP1 phosphorylation after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM87FXPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50185828(CHEMBL3824061)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human GST-tagged PAK1 kinase domain expressed in baculovirus expression system assessed as suppression of phosphorylation o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9DQJPubMed
LigandPNGBDBM50419763(CHEMBL1949921)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50358205(CHEMBL1922090)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 measured after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WMTPubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50097134(CHEMBL3580972)copy SMILES
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1MN9PubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM50097127(CHEMBL3580949)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant PAK4 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1MN9PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50358209(CHEMBL1922095)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 measured after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WMTPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50358207(CHEMBL1922092)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as phosphorylation of recombinant (GFP)-4-EBP1 measured after 30 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WMTPubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Shanghai Chempartner Inc.

Curated by ChEMBL
LigandPNGBDBM101618(US8530652, 114)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant PAK4 (300 to 591 amino acids) using peptide-7 substrate by pyruvate kinase and lactate dehydro...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50096233(CHEMBL3593824)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GWTPubMed
LigandPNGBDBM50347085(CHEMBL1796271)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
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