Compile Data Set for Download or QSAR
Found 138 with Last Name = 'shields' and Initial = 'sd'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521576(CHEMBL4462278)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521582(CHEMBL4543884)copy SMILEScopy InChI
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50466967(CHEMBL4282994)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521579(CHEMBL4543422)copy SMILEScopy InChI
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521586(CHEMBL4473871)copy SMILEScopy InChI
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521571(CHEMBL4464990)copy SMILEScopy InChI
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521573(CHEMBL4519170)copy SMILEScopy InChI
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521569(CHEMBL4446868)copy SMILEScopy InChI
Affinity DataKi:  0.930nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521568(CHEMBL4444408)copy SMILEScopy InChI
Affinity DataKi:  0.970nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521577(CHEMBL4530176)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521585(CHEMBL4557850)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521580(CHEMBL4474681)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521578(CHEMBL4444085)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521587(CHEMBL4569507)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521575(CHEMBL4450910)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521574(CHEMBL4455517)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521581(CHEMBL4462340)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521570(CHEMBL4539134)copy SMILEScopy InChI
Affinity DataKi:  72nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521583(CHEMBL4556147)copy SMILEScopy InChI
Affinity DataKi:  509nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521584(CHEMBL4452003)copy SMILEScopy InChI
Affinity DataKi: >700nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521572(CHEMBL4585581)copy SMILEScopy InChI
Affinity DataKi: >700nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145285(US8952169, 64 | US9771376, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of full length human Nav1.7 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50521568(CHEMBL4444408)copy SMILEScopy InChI
Affinity DataIC50: 0.570nMAssay Description:Inhibition of full length human Nav1.7 expressed in HEK293 cells assessed as reduction of current amplitude at -60 mV holding potential measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CJ3PubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70937(US9546164, 100 | US9694002, 100)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of full length human Nav1.7 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM71064(US9546164, 209 | US9694002, 209)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145285(US8952169, 64 | US9771376, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145369(US8952169, 148 | US9771376, Example 148)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
LigandPNGBDBM452523(1-((3-((3R,5R)-5-(4- chlorophenyl)tetrahydro- fura...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells measured by calcium based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9FKVPubMed
LigandPNGBDBM50573115(CHEMBL4865238)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells measured by calcium based FLIPR assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145281(US8952169, 60 | US9771376, Example 60)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70936(US9546164, 99 | US9694002, 99)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70937(US9546164, 100 | US9694002, 100)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145375(US8952169, 154)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145376(US8952169, 155)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70987(US9546164, 139 | US9694002, 139)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
LigandPNGBDBM50573116(CHEMBL4870870)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells measured by calcium based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9FKVPubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70937(US9546164, 100 | US9694002, 100)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length human Nav1.4 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50587016(CHEMBL5091342)copy SMILES
Affinity DataIC50: 3.60nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50587015(CHEMBL5082739)copy SMILES
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
LigandPNGBDBM50263509(CHEMBL4103545)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as inhibition of cinnamaldehyde-induced Ca2+ influx preincubated for 20 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JZVPubMed
LigandPNGBDBM50263528(CHEMBL4079886)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as inhibition of cinnamaldehyde-induced Ca2+ influx preincubated for 20 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JZVPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145635(US8952169, 440)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
LigandPNGBDBM452523(1-((3-((3R,5R)-5-(4- chlorophenyl)tetrahydro- fura...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Antagonist activity at rat TRPA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9FKVPubMed
LigandPNGBDBM481808(3-[3-(4- chlorophenyl)cyclobutyl]-5- [(7-methyl-6-...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells measured by calcium based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9FKVPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM70981(US9546164, 135 | US9694002, 135)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
LigandPNGBDBM50573116(CHEMBL4870870)copy SMILES
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at rat TRPA1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9FKVPubMed
LigandPNGBDBM50263519(CHEMBL4092287)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human TRPA1 expressed in HEK293 cells assessed as inhibition of cinnamaldehyde-induced Ca2+ influx preincubated for 20 mins followed by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JZVPubMed
LigandPNGBDBM50263519(CHEMBL4092287)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells measured by calcium based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9FKVPubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM145285(US8952169, 64 | US9771376, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Inhibition of full length human Nav1.4 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))TBA
LigandPNGBDBM71126(US9546164, 253 | US9694002, 253)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Displacement of [3H]GX-545 Nav1.7 (unknown origin) expressed in HEK cells by liquid scintillation counting based radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NKSPubMed
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