Compile Data Set for Download or QSAR
Found 375 with Last Name = 'shaik' and Initial = 'tb'
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human HDAC6 using RHKKAc fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50513919(CHEMBL4457162)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517576(CHEMBL4468273)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517583(CHEMBL4556275)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517567(CHEMBL4545246)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7N3HPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054HCPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517585(CHEMBL4443794)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517572(CHEMBL4439108)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517570(CHEMBL4530950)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517574(CHEMBL4444811)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517578(CHEMBL4546254)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human HDAC6 using RHKKAc fluorogenic peptide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517569(CHEMBL4450965)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517577(CHEMBL4442266)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517581(CHEMBL4581606)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517566(CHEMBL4436946)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50578967(CHEMBL4852163)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human HDAC6 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7N3HPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50578975(CHEMBL4870316)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human HDAC6 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7N3HPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50164533(CHEMBL3800182)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054HCPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517568(CHEMBL4438566)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50164532(CHEMBL3797516)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054HCPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517565(CHEMBL4472834)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50164518(CHEMBL3800394)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054HCPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50164532(CHEMBL3797516)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0BQJPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50246866(CHEMBL4078458 | US11505523, Compound 22d)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human HDAC8 (1 to 377 residues) expressed in Escherichia coli BL21(DE3) using Boc-Lys(TFA)-AMC as substrate preincubated for 5 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0BQJPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50164516(CHEMBL3800057)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054HCPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5CJ3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50164517(CHEMBL3798183)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054HCPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517571(CHEMBL4551531)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517573(CHEMBL4436806)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50246847(CHEMBL4089635)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0BQJPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50517579(CHEMBL4442157)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MB7PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50246874(CHEMBL4095643)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0BQJPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human HDAC6 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7N3HPubMedDrugBank
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50246874(CHEMBL4095643)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7N3HPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50468975(CHEMBL4283913)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5CJ3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50468978(CHEMBL4291778)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5CJ3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054HCPubMedDrugBank
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50399672(CHEMBL2178342)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of human His-thioredoxin-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells using Fluor de Lys (R)-HDAC8 as substrate by fluorome...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4FT7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50450625(CHEMBL4160522)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected Sf9 insect cells using Z(Ac)Lys-AMC as substrate by flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4FT7PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50468976(CHEMBL4290685)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5CJ3PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50468974(CHEMBL4295221)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5CJ3PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of human His-thioredoxin-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells using Fluor de Lys (R)-HDAC8 as substrate by fluorome...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164641(CHEMBL3797843)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50246846(CHEMBL4105068)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0BQJPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50578980(CHEMBL4868510)copy SMILES
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7N3HPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50164658(CHEMBL3798268)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054HCPubMed
Displayed 1 to 50 (of 375 total ) | Next | Last >>
Jump to: