Compile Data Set for Download or QSAR
Found 268 with Last Name = 'brown' and Initial = 'tj'
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471498(CHEMBL150450)copy SMILEScopy InChI
Affinity DataKi:  0.240nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471487(CHEMBL436075)copy SMILEScopy InChI
Affinity DataKi:  0.330nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471494(CHEMBL153723)copy SMILEScopy InChI
Affinity DataKi:  0.360nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471485(Vedaclidine)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471499(CHEMBL345774)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471492(CHEMBL150293)copy SMILEScopy InChI
Affinity DataKi:  0.420nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471495(CHEMBL153478)copy SMILEScopy InChI
Affinity DataKi:  0.440nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471486(CHEMBL343731)copy SMILEScopy InChI
Affinity DataKi:  0.450nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033155(3-(3-Butylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471491(CHEMBL357279)copy SMILEScopy InChI
Affinity DataKi:  0.910nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50070725(CHEMBL318403)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003351(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471489(CHEMBL153150)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471496(CHEMBL153031)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033151(3-(3-Hexylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471497(CHEMBL150501)copy SMILEScopy InChI
Affinity DataKi:  9.60nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471488(CHEMBL152892)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471493(CHEMBL152919)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50471490(CHEMBL154923)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Binding affinity against Muscarinic acetylcholine receptors using [3H]oxotremorine-M as radioligand in rat cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ934FPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085853(CHEMBL173251 | Sodium; [2-cyano-5-(pyridin-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065516((R)-4-[2-Cyano-5-(pyridin-3-ylmethoxy)-phenoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065508((R)-4-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-4...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085845(CHEMBL174235 | [5-(Benzooxazol-6-ylmethoxy)-2-cyan...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085859((2-Chloro-phenyl)-[2-cyano-5-(pyridin-4-ylmethoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065523((R)-4-[2-Cyano-5-(isothiazol-4-ylmethoxy)-phenoxy]...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065518(4-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-t...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065524(5-[2-(3-Carboxy-1-o-tolyl-propoxy)-4-(thiophen-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085833(CHEMBL172144 | Sodium; [5-(benzo[1,3]dioxol-5-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065518(4-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-t...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN94SRPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085831(CHEMBL174092 | [2-Cyano-5-(pyridin-4-ylmethoxy)-ph...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085861(CHEMBL170681 | [5-(Benzooxazol-6-ylmethoxy)-2-cyan...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085830(CHEMBL173792 | [5-(Benzo[1,3]dioxol-5-ylmethoxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50329850((R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085838(CHEMBL352536 | [5-(Benzo[1,3]dioxol-5-ylmethoxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085855(CHEMBL170202 | [5-(Benzo[1,3]dioxol-5-ylmethoxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085840((2-Chloro-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065515((R)-4-[2-Cyano-5-(pyridin-4-ylmethoxy)-phenoxy]-4-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085835(CHEMBL427294 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065525(4-[2-(1H-Pyrazol-3-yl)-5-(thiophen-3-ylmethoxy)-ph...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065513(4-[2-Oxazol-2-yl-5-(thiophen-3-ylmethoxy)-phenoxy]...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085854(CHEMBL171638 | [2-Cyano-5-(thiophen-3-ylmethoxy)-p...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085832(CHEMBL171513 | [2-Cyano-5-(2-fluoro-pyridin-4-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065521(4-[2-Acetyl-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065512(4-[2-Carbamoyl-5-(thiophen-3-ylmethoxy)-phenoxy]-4...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM514512(8-(7- (Trifluoromethyl)imidazo[1,5- a]pyridin-5-yl...)copy SMILES
Affinity DataIC50: 29.5nMAssay Description:Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton™ X100, 20 mM ascorbate, 10 μM methylen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6H2FUS Patent
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085839(CHEMBL170348 | [2-Cyano-5-(pyridin-3-ylmethoxy)-ph...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085864(CHEMBL354740 | [2-Cyano-5-(thiazol-5-ylmethoxy)-ph...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065520(4-[2-Pyridin-2-yl-5-(thiophen-3-ylmethoxy)-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of [125I]ET1 binding to rat A10 cell Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM594WPubMed
TargetEndothelin-1 receptor(RAT)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085856(CHEMBL355413 | [5-(Benzo[1,3]dioxol-5-ylmethoxy)-2...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154G73PubMed
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