Compile Data Set for Download or QSAR
Found 162 with Last Name = 'yan' and Initial = 'tp'
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM50277188(CHEMBL473270 | N1-(biphenyl-3-yl)-N8-hydroxyoctane...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged HDAC1 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WXBPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50277188(CHEMBL473270 | N1-(biphenyl-3-yl)-N8-hydroxyoctane...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WXBPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255852(4-(((R)-3-(4-hydroxybenzyl)-2,3-dihydro-2-oxoquino...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255096(4-(((R)-3-benzyl-2,3-dihydro-2-oxoquinoxalin-4(1H)...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255853(4-(((R)-2,3-dihydro-2-oxo-3-phenethylquinoxalin-4(...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19412(CHEMBL235674 | benzamide-type inhibitor, 4 | pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19423(HDAC inhibitor, Compound 1 | N-[2-amino-5-(thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19421(4-{[(3,4-dimethoxyphenyl)amino]methyl}-N-[2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255854((R)-tert-butyl 4-(1-(4-(hydroxycarbamoyl)benzyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255809(4-(((R)-3-(3,4-difluorobenzyl)-2,3-dihydro-2-oxoqu...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255914(4-(((R)-2,3-dihydro-2-oxo-3-((thiophen-2-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19416(N-[2-amino-5-(thiophen-3-yl)phenyl]-4-{[(3,4-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255910(4-(((R)-3-(4-tert-butoxybenzyl)-2,3-dihydro-2-oxoq...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19414(N-[2-amino-5-(thiophen-2-yl)phenyl]-4-{[(3,4-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19427(N-[2-amino-5-(thiophen-2-yl)phenyl]-4-methoxybenza...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19417(N-[2-amino-5-(furan-3-yl)phenyl]-4-{[(3,4-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19415(N-(2-amino-5-phenylphenyl)-4-{[(3,4-dimethoxypheny...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19421(4-{[(3,4-dimethoxyphenyl)amino]methyl}-N-[2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19425(N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-c...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50277329((S)-benzyl 1-(6-methoxyquinolin-8-ylamino)-1-oxo-6...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WXBPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19416(N-[2-amino-5-(thiophen-3-yl)phenyl]-4-{[(3,4-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19417(N-[2-amino-5-(furan-3-yl)phenyl]-4-{[(3,4-dimethox...)copy SMILEScopy InChI
Affinity DataIC50: 70nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19414(N-[2-amino-5-(thiophen-2-yl)phenyl]-4-{[(3,4-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 80nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19423(HDAC inhibitor, Compound 1 | N-[2-amino-5-(thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged HDAC1 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19415(N-(2-amino-5-phenylphenyl)-4-{[(3,4-dimethoxypheny...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19412(CHEMBL235674 | benzamide-type inhibitor, 4 | pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255912(4-(((R)-2-((1H-indol-3-yl)methyl)-3,6-dioxopiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255097(4-((2,3-dihydro-2-oxoquinoxalin-4(1H)-yl)methyl)-N...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM50256888((S)-benzyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged HDAC1 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WXBPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255913(CHEMBL481726 | N-hydroxy-4-(((R)-3,6-dioxo-2-((thi...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255911(4-(((R)-2-benzyl-3,6-dioxopiperazin-1-yl)methyl)-N...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50256888((S)-benzyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WXBPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19427(N-[2-amino-5-(thiophen-2-yl)phenyl]-4-methoxybenza...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WXBPubMedDrugBank
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19420(4-{[(3,4-dimethoxyphenyl)amino]methyl}-N-(2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 200nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19425(N-[2-amino-5-(thiophen-2-yl)phenyl]quinoxaline-6-c...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
MethylGene Inc

Curated by ChEMBL
LigandPNGBDBM50255095(4-(((S)-3-benzyl-2,3-dihydro-2-oxoquinoxalin-4(1H)...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant histone deacetylase 8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255095(4-(((S)-3-benzyl-2,3-dihydro-2-oxoquinoxalin-4(1H)...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
MethylGene Inc

Curated by ChEMBL
LigandPNGBDBM50255910(4-(((R)-3-(4-tert-butoxybenzyl)-2,3-dihydro-2-oxoq...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant histone deacetylase 8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM50255096(4-(((R)-3-benzyl-2,3-dihydro-2-oxoquinoxalin-4(1H)...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM19420(4-{[(3,4-dimethoxyphenyl)amino]methyl}-N-(2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 300nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50255851(4-(((S)-2,3-dihydro-2-oxo-3-((thiophen-2-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
MethylGene Inc

LigandPNGBDBM50255852(4-(((R)-3-(4-hydroxybenzyl)-2,3-dihydro-2-oxoquino...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44Q5SPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
MethylGene Inc.

Curated by ChEMBL
LigandPNGBDBM50277289(CHEMBL507114 | N-(quinolin-8-yl)-6-(sulfamoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416WXBPubMed
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