Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 2' and Ligand = 'BDBM19428'
TargetHistone deacetylase 2(Homo sapiens (Human))
St Jude Children's Research Hospital

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B859V9PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
St Jude Children's Research Hospital

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445JS2PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
St Jude Children's Research Hospital

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant C-terminal FLAG-tagged HDAC2 expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ87QHPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
St Jude Children's Research Hospital

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human HDAC2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8KZJPubMed