Compile Data Set for Download or QSAR
Found 88 with Last Name = 'zwick' and Initial = 'v'
TargetHistone deacetylase 1/2/3(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of HDAC1/HDAC2/HDAC3 in human HeLa nuclear extracts using MAL as substrate after 4 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Inhibition of HDAC1 (unknown origin) after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X3502TPubMed
TargetHistone deacetylase(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of HDAC in human HeLa cell extract after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of HDAC6 in human SHSY5Y cells using BATCP as substrate after 8 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of HDAC6 (unknown origin) after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using MOCPAC as substrate after 4 hrs by UHPLC-ES...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant HDAC6 expressed in baculovirus infected insect cells using BATCP as substrate after 4 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC1 in human SHSY5Y cells using MOCPAC as substrate after 8 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of HDAC2 (unknown origin) after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X3502TPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells using RHK-K(Ac)-AMC as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMedDrugBank
TargetHistone deacetylase 7(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged HDAC7 (518 to 991 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate incubate...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant HDAC6 expressed in baculovirus infected insect cells using BATCP as substrate after 4 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50197083(CHEMBL3890846)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant HDAC6 expressed in baculovirus infected insect cells using BATCP as substrate after 4 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC6 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GCPPubMedDrugBank
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of HDAC6 in human SHSY5Y cells using BATCP as substrate after 8 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant HDAC2 using Fluor de Lys Green as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC3 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GCPPubMedDrugBank
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50197083(CHEMBL3890846)copy SMILEScopy InChI
Affinity DataIC50: 164nMAssay Description:Inhibition of HDAC6 in human SHSY5Y cells using BATCP as substrate after 8 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 1/2/3(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50197083(CHEMBL3890846)copy SMILEScopy InChI
Affinity DataIC50: 188nMAssay Description:Inhibition of HDAC1/HDAC2/HDAC3 in human HeLa nuclear extracts using MAL as substrate after 4 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC8 (1 to 377 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate incubated ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells using RHK-K(Ac)-AMC as subst...More data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using BOC-Ac-Lys-AMC as substrate incubated for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of human HDAC9 using RHK-K(Ac)-AMC as substrate incubated for 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of full length human recombinant C-terminal His-tagged HDAC3 (1 to 428 residues)/human recombinant N-terminal GST-tagged NCOR2 (395 to 489...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of HDAC1 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant N-terminal His-tagged HDAC11 (1 to 347 residues) using RHK-K(Ac)-AMC as substrate incubated for 60 mins by fluorescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC5 (657 to 1123 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of human HDAC10 using RHK-K(Ac)-AMC as substrate incubated for 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant C-terminal His-tagged, N-terminal GST-tagged HDAC4 (627 to 1084 residues) expressed in insect cells using RHK-K(Ac)-A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of HDAC2 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50197083(CHEMBL3890846)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of human recombinant GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using MOCPAC as substrate after 4 hrs by UHPLC-ES...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM50161828(CHEMBL3793310)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC8 (1 to 377 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50197083(CHEMBL3890846)copy SMILEScopy InChI
Affinity DataIC50: 973nMAssay Description:Inhibition of HDAC1 in human SHSY5Y cells using MOCPAC as substrate after 8 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50161828(CHEMBL3793310)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells using RHK-K(Ac)-AMC as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of HDAC1 in human SHSY5Y cells using MOCPAC as substrate after 8 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50161828(CHEMBL3793310)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using BOC-Ac-Lys-AMC as substrate incubated for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 1/2/3(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HDAC1/HDAC2/HDAC3 in human HeLa nuclear extracts using MAL as substrate after 4 hrs by UHPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using MOCPAC as substrate after 4 hrs by UHPLC-ES...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0B78PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50115661(CHEMBL320497 | N,8-dihydroxy-8-(hydroxyamino)octan...)copy SMILEScopy InChI
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GCPPubMed
TargetHistone deacetylase(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50161468(CHEMBL3794127)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HDAC in human HeLa cells using BOC-Ac-Lys-AMC as substrate incubated for 4 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50161468(CHEMBL3794127)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using BOC-Ac-Lys-AMC as substrate incubated for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50499957(CHEMBL3739529)copy SMILEScopy InChI
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GCPPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM19422(4-(acetylamino)-N-(2-amino-phenyl) benzamide | CI-...)copy SMILEScopy InChI
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GCPPubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM50161828(CHEMBL3793310)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of full length human recombinant C-terminal His-tagged HDAC3 (1 to 428 residues)/human recombinant N-terminal GST-tagged NCOR2 (395 to 489...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50036932(CHEMBL1478023 | US11866416, Compound SN-II-118)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X3502TPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50161828(CHEMBL3793310)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Fluor de Lys Green as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50161828(CHEMBL3793310)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells using RHK-K(Ac)-AMC as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50115661(CHEMBL320497 | N,8-dihydroxy-8-(hydroxyamino)octan...)copy SMILEScopy InChI
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1GCPPubMed
TargetHistone deacetylase(Homo sapiens (Human))
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50161828(CHEMBL3793310)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of HDAC in human HeLa cells using BOC-Ac-Lys-AMC as substrate incubated for 4 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University of Milan

Curated by ChEMBL
LigandPNGBDBM50161828(CHEMBL3793310)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC5 (657 to 1123 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5BB0PubMed
Displayed 1 to 50 (of 88 total ) | Next | Last >>
Jump to: