Compile Data Set for Download or QSAR
Found 108 with Last Name = 'sommergruber' and Initial = 'w'
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519121(CHEMBL4436264 | US11304929, Example 03-005)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519122(CHEMBL4467246 | US11304929, Example 03-009)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519130(CHEMBL4520837 | US11304929, Example 03-006)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519121(CHEMBL4436264 | US11304929, Example 03-005)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519122(CHEMBL4467246 | US11304929, Example 03-009)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519137(CHEMBL4539932)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of His6-tagged PHGDH (unknown origin) expressed in Escherichia coli BL21 assessed as effect on NADH fluorescence incubated for 60 mins usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse GST-fused VEGFR2 expressed in Sf9 insect cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519120(CHEMBL4438014)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human LckMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human GST-fused VEGFR2 expressed in Sf9 insect cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519114(CHEMBL4458393 | US11304929, Example 04-001)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human Flt3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519150(CHEMBL4594097)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519093(CHEMBL4522467)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519131(CHEMBL4518579 | US11304929, Example 01-002)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of PHGDH in human MDA-MB-468 cells assessed as reduction in [13C]-serine incubated for 1 hr using [13C]glucose as substrate by LC-MS/MS an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519118(CHEMBL4473052)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519090(CHEMBL4469992)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human FGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519117(CHEMBL4474620)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519116(CHEMBL4457646)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519129(CHEMBL4560125)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519136(CHEMBL4565713)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519092(CHEMBL4437057)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519119(CHEMBL4444192)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519120(CHEMBL4438014)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519108(CHEMBL4446190)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519134(CHEMBL4588817)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Inhibition of human FGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519153(CHEMBL4460522)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Inhibition of human SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 195nMAssay Description:Inhibition of human LynMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519090(CHEMBL4469992)copy SMILEScopy InChI
Affinity DataIC50: 228nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519150(CHEMBL4594097)copy SMILEScopy InChI
Affinity DataIC50: 246nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519093(CHEMBL4522467)copy SMILEScopy InChI
Affinity DataIC50: 249nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519149(CHEMBL4446511)copy SMILEScopy InChI
Affinity DataIC50: 254nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519148(CHEMBL4528650)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519118(CHEMBL4473052)copy SMILEScopy InChI
Affinity DataIC50: 301nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519129(CHEMBL4560125)copy SMILEScopy InChI
Affinity DataIC50: 341nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519116(CHEMBL4457646)copy SMILEScopy InChI
Affinity DataIC50: 345nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519101(CHEMBL4435368)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519117(CHEMBL4474620)copy SMILEScopy InChI
Affinity DataIC50: 412nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Boehringer Ingelheim Austria GmbH

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of human FGFR4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3715PubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519119(CHEMBL4444192)copy SMILEScopy InChI
Affinity DataIC50: 714nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519092(CHEMBL4437057)copy SMILEScopy InChI
Affinity DataIC50: 746nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Boehringer Ingelheim RCV GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50519096(CHEMBL4561620)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7KNJPubMed
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