Compile Data Set for Download or QSAR
Found 93 with Last Name = 'sly' and Initial = 'ws'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11404(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nM ΔG°:  -59.9kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11422(2-(3,4-Dimethoxyphenyl)-3-[(4-morpholinyl)methyl]-...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11399(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11408(1,1-dioxo-3-[(prop-2-yn-1-ylamino)methyl]-2-propyl...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11419(2-[(4-Methoxyphenyl)methyl]-3-[(4-morpholinyl)meth...)copy SMILEScopy InChI
Affinity DataKi:  0.110nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11421(2-(3-Methoxyphenyl)-3-[(2-hydroxyethylamino)methyl...)copy SMILEScopy InChI
Affinity DataKi:  0.110nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11418(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11423(2-[(4-Morpholinyl)phenyl]-3-[(4-morpholinyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM10885((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)copy SMILEScopy InChI
Affinity DataKi:  0.130nM ΔG°:  -58.7kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11407(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataKi:  0.150nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11391(2-(3-Methoxyphenyl)-3-[(4-morpholinyl)methyl]-2H-t...)copy SMILEScopy InChI
Affinity DataKi:  0.150nM ΔG°:  -58.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11390(2-(3-Hydroxyphenyl)-3-(4-morpholinylmethyl)-2H-thi...)copy SMILEScopy InChI
Affinity DataKi:  0.150nM ΔG°:  -58.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11398(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataKi:  0.150nM ΔG°:  -58.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11411(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11425(2-(3-Hydroxyphenyl)-3-[(2-propynylamino)methyl]-2H...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11424(2-(3-Hydroxypropyl)-3-(4-morpholinylmethyl)-2H-thi...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11400(2-Ethyl-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]...)copy SMILEScopy InChI
Affinity DataKi:  0.210nM ΔG°:  -57.5kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11401(2-Ethyl-3-[[bis(2-methoxyethyl)amino]methyl]-2H-th...)copy SMILEScopy InChI
Affinity DataKi:  0.210nM ΔG°:  -57.5kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11426(2-Methyl-3-(4-morpholinylmethyl)-2H-thieno[2,3-e]-...)copy SMILEScopy InChI
Affinity DataKi:  0.210nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11415(2-(2-Methoxyethyl)-3-[[bis(2-methoxyethyl)amino]me...)copy SMILEScopy InChI
Affinity DataKi:  0.210nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11414(2-(2-Methoxyethyl)-3-[(4-morpholinyl)methyl]-2H-th...)copy SMILEScopy InChI
Affinity DataKi:  0.220nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11403(2-[(2E)-4-(morpholin-4-yl)but-2-en-1-yl]-1,1-dioxo...)copy SMILEScopy InChI
Affinity DataKi:  0.240nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11416(2-(3-Methoxypropyl)-3-[(4-morpholinyl)methyl]-2H-t...)copy SMILEScopy InChI
Affinity DataKi:  0.25nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11395(2-[2-(4-acetylpiperazin-1-yl)ethyl]-1,1-dioxo-2H-1...)copy SMILEScopy InChI
Affinity DataKi:  0.25nM ΔG°:  -57.0kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11417(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11397(2-Methyl-3-(4-morpholinylmethyl)-2H-thieno[3,2-e]-...)copy SMILEScopy InChI
Affinity DataKi:  0.260nM ΔG°:  -56.9kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11406(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11412(2-(cyclopropylmethyl)-3-(morpholin-4-ylmethyl)-1,1...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11413(2-Cyclohexyl-3-[(4-morpholinyl)methyl]-2H-thieno[3...)copy SMILEScopy InChI
Affinity DataKi:  0.310nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11394(2-[2-(4-Morpholinyl)ethyl]-2H-thieno[3,2-e]-1,2-th...)copy SMILEScopy InChI
Affinity DataKi:  0.320nM ΔG°:  -56.4kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11409(2-(1-Methylethyl)-3-[(4-morpholinyl)methyl]-2H-thi...)copy SMILEScopy InChI
Affinity DataKi:  0.330nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11405(2-Ethyl-3-[[bis(2-hydroxyethyl)amino]methyl]-2H-th...)copy SMILEScopy InChI
Affinity DataKi:  0.330nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11393(2-[2-[Bis(2-methoxyethyl)amino]ethyl]-2H-thieno[3,...)copy SMILEScopy InChI
Affinity DataKi:  0.340nM ΔG°:  -56.2kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11410(1,1-dioxo-3-[(prop-2-yn-1-ylamino)methyl]-2-(propa...)copy SMILEScopy InChI
Affinity DataKi:  0.470nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)copy SMILEScopy InChI
Affinity DataKi:  0.510nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11396(1,1-dioxo-2-[2-(propylamino)ethyl]-2H-1,7,2-thieno...)copy SMILEScopy InChI
Affinity DataKi:  0.520nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11425(2-(3-Hydroxyphenyl)-3-[(2-propynylamino)methyl]-2H...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11413(2-Cyclohexyl-3-[(4-morpholinyl)methyl]-2H-thieno[3...)copy SMILEScopy InChI
Affinity DataIC50: 0.790nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11394(2-[2-(4-Morpholinyl)ethyl]-2H-thieno[3,2-e]-1,2-th...)copy SMILEScopy InChI
Affinity DataIC50: 0.820nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11393(2-[2-[Bis(2-methoxyethyl)amino]ethyl]-2H-thieno[3,...)copy SMILEScopy InChI
Affinity DataIC50: 0.910nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11405(2-Ethyl-3-[[bis(2-hydroxyethyl)amino]methyl]-2H-th...)copy SMILEScopy InChI
Affinity DataIC50: 0.960nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11395(2-[2-(4-acetylpiperazin-1-yl)ethyl]-1,1-dioxo-2H-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.960nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11411(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataIC50: 0.990nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11401(2-Ethyl-3-[[bis(2-methoxyethyl)amino]methyl]-2H-th...)copy SMILEScopy InChI
Affinity DataIC50: 1.04nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11422(2-(3,4-Dimethoxyphenyl)-3-[(4-morpholinyl)methyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 1.05nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11400(2-Ethyl-3-[(4-morpholinyl)methyl]-2H-thieno[3,2-e]...)copy SMILEScopy InChI
Affinity DataIC50: 1.11nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11399(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.11nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11390(2-(3-Hydroxyphenyl)-3-(4-morpholinylmethyl)-2H-thi...)copy SMILEScopy InChI
Affinity DataIC50: 1.15nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11421(2-(3-Methoxyphenyl)-3-[(2-hydroxyethylamino)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.16nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11398(2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.17nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
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