Compile Data Set for Download or QSAR
Found 37 Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-15'
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102594(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexade...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of matrix metalloprotease-15More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50102608(11-Isobutyl-2,10-dioxo-1-oxa-3,9-diaza-cyclopentad...)copy SMILEScopy InChI
Affinity DataKi:  71nMAssay Description:Inhibition of matrix metalloprotease-15More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB53NRPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50265114(CHEMBL495502 | N-((2R,6S)-4-(2-(hydroxyamino)-2-ox...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104975((8S,11R,12S)-2,10-Dioxo-11-(2'-trifluoromethyl-bip...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104976(11-(3',5'-Bis-trifluoromethyl-biphenyl-4-ylmethyl)...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-15More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104975((8S,11R,12S)-2,10-Dioxo-11-(2'-trifluoromethyl-bip...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-15More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104973(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-15More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-15More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM26526((2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylqui...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Affinity for Matrix metalloprotease-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP7497PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM26526((2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylqui...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50183711(CHEMBL208009 | N-(4-(2-(hydroxyamino)-2-oxoethyl)p...)copy SMILEScopy InChI
Affinity DataKi: >7.09E+3nMAssay Description:Binding affinity to MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16H3PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50183715(CHEMBL207305 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)copy SMILEScopy InChI
Affinity DataKi: >7.09E+3nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50183715(CHEMBL207305 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)copy SMILEScopy InChI
Affinity DataKi: >7.09E+3nMAssay Description:Binding affinity to MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16H3PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM26575((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)py...)copy SMILEScopy InChI
Affinity DataKi: >7.09E+3nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50229322((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)copy SMILEScopy InChI
Affinity DataKi: >7.10E+3nMAssay Description:Binding affinity to MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7HGGPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50365344(CHEMBL1956115)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0H0WPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM26806((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03C3PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137287(2-Benzenesulfonyl-6-benzyloxy-1,2,3,4-tetrahydro-i...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137282(6-Hydroxy-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137281(2-Benzenesulfonyl-6-hydroxy-7-methoxy-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137285(6-(benzyloxy)-N-hydroxy-2-tosyl-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)copy SMILEScopy InChI
Affinity DataIC50: 218nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 385nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 621nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137278(2-(2,5-Dichloro-benzenesulfonyl)-6-hydroxy-1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.79E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137278(2-(2,5-Dichloro-benzenesulfonyl)-6-hydroxy-1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50265157((6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4WM2PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50204392((3R,4R)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9BF4PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50137280(6-Benzyloxy-2-(2,5-dichloro-benzenesulfonyl)-1,2,3...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP15 (unknown origin) catalytic domain using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3N0FPubMedDrugBank
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50180601(3-(4-(2-phenylethynyl)benzoyl)pentanoic acid | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibitory activity against MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03C3PubMed