Compile Data Set for Download or QSAR
Found 80 Enz. Inhib. hit(s) with Target = 'Nuclear receptor subfamily 2 group C member 2'
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375312(US9908872, Compound (I-9))copy SMILEScopy InChI
Affinity DataIC50: 2.43nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375310(US9908872, Compound (I-8))copy SMILEScopy InChI
Affinity DataIC50: 5.33nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375276(US10597387, Compound (I-1) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
LigandPNGBDBM50042034((5Z)-7-Oxozeaenol | 5Z-7-Oxozeaenol | CHEBI:67559 ...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Tak1/Tab1 (unknown origin) assessed as inhibition of Tak1 kinase activity preincubated for 30 mins followed by addition of MBP protein ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4G11PubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50379186(CEP-11981 | CHEMBL2010872)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human TAK1 using ATP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XHWPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375281(US10597387, Compound (I-4) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 22.8nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375307(US10597387, Compound (I-6) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 29.9nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
LigandPNGBDBM50129131(CHEBI:83275 | Hypothemycin | US10434085, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N854CPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439303(US10633348, Compound (A-17))copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439318(US10633348, Compound (A-14))copy SMILEScopy InChI
Affinity DataIC50: 53.8nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375308(US10597387, Compound (I-7) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 56.5nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50086441(CHEMBL3426225 | US10266537, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of human TAK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38V91PubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375280(US10597387, Compound (I-3) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 62.2nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439308(US10633348, Compound (A-6))copy SMILEScopy InChI
Affinity DataIC50: 63.5nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439309(US10633348, Compound (A-7))copy SMILEScopy InChI
Affinity DataIC50: 71.7nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439316(US10633348, Compound (A-12))copy SMILEScopy InChI
Affinity DataIC50: 76.2nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439305(US10633348, Compound (A-3))copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439307(US10633348, Compound (A-5))copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439304(US10633348, Compound (A-2))copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375299(US10597387, Compound (I-5) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 117nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50604141(CHEMBL5188433)copy SMILES
Affinity DataIC50: 120nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50584720(CHEMBL5088153)copy SMILES
Affinity DataIC50: 126nMAssay Description:Inhibition of human TAK1 in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2377DMNPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439319(US10633348, Compound (A-15))copy SMILEScopy InChI
Affinity DataIC50: 136nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50604140(CHEMBL5185000)copy SMILES
Affinity DataIC50: 260nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM438001(US10633348, Compound (A-1) | US10633348, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 364nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439317(US10633348, Compound (A-13))copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM438001(US10633348, Compound (A-1) | US10633348, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 487nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
LigandPNGBDBM50574560(CHEMBL4848326)copy SMILES
Affinity DataIC50: 580nMAssay Description:Inhibition of Tak1/Tab1 (unknown origin) assessed as inhibition of Tak1 kinase activity preincubated for 30 mins followed by addition of MBP protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4G11PubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439306(US10633348, Compound (A-4))copy SMILEScopy InChI
Affinity DataIC50: 591nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)copy SMILEScopy InChI
Affinity DataIC50: 717nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8W63US Patent
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