Compile Data Set for Download or QSAR
Found 182 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma'
LigandPNGBDBM50193032(CHEMBL3979343 | US11155556, No. 2)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50193014(CHEMBL3942643 | US11155556, No. 9)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50193031(CHEMBL3959351 | US11155556, No. 12)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50193017(CHEMBL3904942 | US11155556, No. 17)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50193016(CHEMBL3889977 | US11155556, No. 3)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50193023(CHEMBL3898901 | US11155556, No. 5)copy SMILEScopy InChI
Affinity DataIC50: 29.3nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50193030(CHEMBL3950648 | US11155556, No. 14)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50193020(CHEMBL3907932 | US11155556, No. 7)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50193021(CHEMBL3922919 | US11155556, No. 13)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50337135(4-((5,11-dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]py...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50193018(CHEMBL3986648 | US11155556, No. 10)copy SMILEScopy InChI
Affinity DataIC50: 50.7nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50512861(CHEMBL4558527)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of PIK3C2G (unknown origin) assessed as reduction in substrate phosphorylation by FRET Adapta assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZVJPubMed
LigandPNGBDBM50193029(CHEMBL3913941 | US11155556, No. 15)copy SMILEScopy InChI
Affinity DataIC50: 75.9nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM50193012(CHEMBL3926951 | US11155556, No. 6)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20868G7US Patent
LigandPNGBDBM657180(3-amino-6-(5-((S)-1,1-difluoro-2,3- dihydroxypropa...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657181(3-Amino-N-(4-cyanobicyclo[2.1.1]hexan-1-yl)-6-(5-(...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657025(2-(3-(5-Amino-6-(1-(methyl-d3)-1H-pyrazol-5-yl)pyr...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657047(2-(3-(5-Amino-6-(1-methyl-1H-pyrazol-4- yl)pyrazin...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657048(2-(3-(5-Amino-6-(1H-pyrazol-4-yl)pyrazin- 2-yl)-4-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657049(2-(3-(5-Amino-6-(3-methylisoxazol-5- yl)pyrazin-2-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657052(2-(3-(5-Amino-6-(isothiazol-4-yl)pyrazin-2- yl)-4-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657053(2-(3-(5-Amino-6-(isothiazol-5-yl)pyrazin-2- yl)-4-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657056(2-(3-(5-amino-6-(3-methylisothiazol-5- yl)pyrazin-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657065(2-(3-(5-Amino-6-(2-methyloxazol-5-yl)pyrazin-2-yl)...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657067(2-(3-(5-Amino-6-(2-methylthiazol-5-yl)pyrazin- 2-y...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657069(2-(3-(5-Amino-6-(oxazol-5-yl)pyrazin-2-yl)-4- meth...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657080(2-(3-(5-Amino-6-(1H-pyrazol-1-yl)pyrazin-2-yl)-4-m...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657081(2-(3-(5-Amino-6-(1H-1,2,3-triazol-1-yl)pyrazin- 2-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657085(2-(3-(5-Amino-6-(1H-1,2,3-triazol-2-yl)pyrazin- 2-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657092(2-(3-(5-Amino-6-(1H-1,2,4-triazol-1-yl)pyrazin- 2-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657098(2-(3-(5-Amino-6-(2-methyloxazol-5-yl)pyrazin-2-yl)...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657107(3-Amino-6-(2-(methyl-d3)-5-(1,1,1-trifluoro-2,3-di...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657108(3-Amino-6-(5-(1,1-difluoro-2,3-dihydroxypropan-2-y...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657115(3-Amino-6-(2-(methyl-d3)-5-(1,1,1-trifluoro-2,3-di...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657117(2-(3-(5-Amino-6-(3-methyl-1H-pyrazol-4-yl)pyrazin-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657117(2-(3-(5-Amino-6-(3-methyl-1H-pyrazol-4-yl)pyrazin-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657143(3-Amino-6-(2-methyl-5-(1,1,1-trifluoro-2,3-dihydro...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657146(2-(3-(5-Amino-6-(1-((1-methyl-1H-pyrazol-3-yl)sulf...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657147((3-(3-Amino-6-(2-methyl-5-(1,1,1-trifluoro-2,3-dih...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657148(2-(3-(5-Amino-6-(trifluoromethyl)pyrazin-2-yl)-4-m...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657152(3-Amino-N-((1s,3R)-3-cyanocyclobutyl)-6- (2-(methy...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657153(3-Amino-N-((1S,2S)-2- hydroxycyclohexyl)-6-(2-(met...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657154(3-Amino-N-((trans)-3-hydroxytetrahydro- 2H-pyran-4...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657155(3-Amino-N-((1s,3R)-3-hydroxy-3- (trifluoromethyl)c...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657157(3-Amino-N-((1s,3R)-3-hydroxy-1- methylcyclobutyl)-...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657158((S)-3-Amino-N-(4- (hydroxymethyl)bicyclo[2.1.l]hex...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657159((S)-3-Amino-N-(3- (hydroxymethyl)bicyclo[1.1.1]pen...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657160(3-Amino-N-((S)-1-hydroxypropan-2-yl)-6- (2-(methyl...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657161((S)-3-Amino-N-(2-cyano-2-methylpropyl)- 6-(2-(meth...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM657162((S)-3-Amino-N-(4- hydroxybicyclo[2.2.1]heptan-1-yl...)copy SMILES
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
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