Compile Data Set for Download or QSAR
Found 58 Enz. Inhib. hit(s) with Target = 'Somatostatin receptor type 1/2/3/4/5'
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50187377(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity to somatostatin receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319VHCPubMed
LigandPNGBDBM50214420(CHEMBL330352)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3NBX
LigandPNGBDBM50214420(CHEMBL330352)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3NBX
LigandPNGBDBM50214420(CHEMBL330352)copy SMILEScopy InChI
Affinity DataKi:  6.31E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3NBX
LigandPNGBDBM50212468(CHEMBL28415)copy SMILEScopy InChI
Affinity DataKi:  1.86E+4nMAssay Description:Inhibitory activity against Somatostatin receptor in rat cortex membrane using 125 I-Tyrs-octreotide as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350M0
LigandPNGBDBM50476140(CHEMBL373632)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
LigandPNGBDBM81767(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9166
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50476134(CHEMBL437296)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Mus musculus)
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Displacement of [125I]Tyr11-somatostatin-14 from mouse SST receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6FPCPubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50476138(CHEMBL376485)copy SMILEScopy InChI
Affinity DataIC50: 0.350nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
LigandPNGBDBM50476137(CHEMBL222751)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
LigandPNGBDBM81767(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3NBX
LigandPNGBDBM50214421(SOMATOSTATIN RECEPTOR LIGAND)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3NBX
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50212467(Sandostatinm)copy SMILEScopy InChI
Affinity DataIC50: 0.460nMAssay Description:Compound was tested for free energy of binding against somatostatin receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350M0
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50476142(CHEMBL376484)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50476141(CHEMBL426548)copy SMILEScopy InChI
Affinity DataIC50: 0.640nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
LigandPNGBDBM50476135(CHEMBL374316)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50192018(CHEMBL3350037)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
LigandPNGBDBM50476143(CHEMBL376001)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50476136(CHEMBL222699)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50476139(CHEMBL268060)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50008923((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PC3PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50222716(CHEMBL2371535)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PC3PubMed
LigandPNGBDBM50476144(CHEMBL434761)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9FK5PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50222720(CHEMBL2371563)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PC3PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50222719(CHEMBL2371564)copy SMILEScopy InChI
Affinity DataIC50: 571nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PC3PubMed
LigandPNGBDBM50020202(CHEMBL2369466 | D-Tic-c(Cys-Tyr-D-Trp-Lys-Thr-Pen-...)copy SMILEScopy InChI
Affinity DataIC50: 949nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50222717(CHEMBL2371567)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PC3PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50222718(CHEMBL2371562)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3PC3PubMed
TargetSomatostatin receptor type 1/2/3/4/5(Mus musculus)
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM81767(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Compound was tested for its binding affinity against somatostatin receptors on AtT-20 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350M0
LigandPNGBDBM50020209(CHEMBL410090 | CTP)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50020205(CHEMBL216354 | D-Tic-c(Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50020213(CHEMBL264082 | D-Trpc(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50020211(CHEMBL216353 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50020216(CHEMBL413831 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.89E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50020198(CHEMBL308471 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50020200(CHEMBL405672 | D-Ticc(-Cys-Tyr-D-Typ-Lys-Thr-Pen-)...)copy SMILEScopy InChI
Affinity DataIC50: 1.99E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50020214(CHEMBL302596 | D-Phec(-Cys-Tyr-D-Trp-Lys-D-Pen-)Th...)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50214420(CHEMBL330352)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3NBX
LigandPNGBDBM50214420(CHEMBL330352)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3NBX
LigandPNGBDBM50214420(CHEMBL330352)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3NBX
LigandPNGBDBM50020199(CHEMBL441164 | D-N-Me-Phec(-Cys-Tyr-D-Trp-Orn-Thr-...)copy SMILEScopy InChI
Affinity DataIC50: 8.05E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50020212(CHEMBL405244 | D-Phec(-Cys-Tyr-D-Trp-Lys-Thr-Pen-)...)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50020208(CHEMBL1795717 | TCTAP)copy SMILEScopy InChI
Affinity DataIC50: 8.45E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50020204(CHEMBL66403 | D-Phec(-Cys-Tyr-Asn-Pen-)Thr-NH2)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
LigandPNGBDBM50213874(CHEMBL432503)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9166
LigandPNGBDBM50213872(CHEMBL47019)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9166
LigandPNGBDBM50213869(CHEMBL3037859)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9166
LigandPNGBDBM50213871(CHEMBL47648)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9166
LigandPNGBDBM50452485(CHEMBL2369462)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+4nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RJXPubMed
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