TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity to somatostatin receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.31E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.86E+4nMAssay Description:Inhibitory activity against Somatostatin receptor in rat cortex membrane using 125 I-Tyrs-octreotide as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Displacement of [125I]Tyr11-somatostatin-14 from mouse SST receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Compound was tested for free energy of binding against somatostatin receptorMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranesMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranesMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I-Tyr-11]-SRIF from SSTR of human NCI-H69 cell membranesMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranesMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 571nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
Affinity DataIC50: 949nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 1/2/3/4/5(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Cytotoxic activity against human neuroblastoma IMR32 cells which over-express somatostatin receptorsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Compound was tested for its binding affinity against somatostatin receptors on AtT-20 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.46E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.94E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.99E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 8.05E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 8.45E+3nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+4nMAssay Description:Binding affinity in competition with [125I]- CGP-23996 in somatostatin receptor binding to rat brain membraneMore data for this Ligand-Target Pair