Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Thiamine transporter ThiT'
TargetThiamine transporter ThiT(Lactococcus lactis (Firmicutes))
University of Groningen

LigandPNGBDBM50373886(3-Deazathiamine | CHEMBL401772)copy SMILEScopy InChI
Affinity DataKd:  4.23nMAssay Description:Purified ThiT was diluted in buffer E to a concentration of ~50 nM in a final volume of 800 無. The substrates were added in 1 無 steps. Using an exc...More data for this Ligand-Target Pair
TargetThiamine transporter ThiT(Lactococcus lactis (Firmicutes))
University of Groningen

LigandPNGBDBM150801((3-((4-Amino-2-methylpyrimidin-5-yl)methyl)phenyl)...)copy SMILEScopy InChI
Affinity DataKd:  266nMAssay Description:Purified ThiT was diluted in buffer E to a concentration of ~50 nM in a final volume of 800 無. The substrates were added in 1 無 steps. Using an exc...More data for this Ligand-Target Pair
TargetThiamine transporter ThiT(Lactococcus lactis (Firmicutes))
University of Groningen

LigandPNGBDBM150804(4-((4-Amino-2-methylpyrimidin-5-yl)methyl)-3-methy...)copy SMILEScopy InChI
Affinity DataKd:  7.44nMAssay Description:Purified ThiT was diluted in buffer E to a concentration of ~50 nM in a final volume of 800 無. The substrates were added in 1 無 steps. Using an exc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetThiamine transporter ThiT(Lactococcus lactis (Firmicutes))
University of Groningen

LigandPNGBDBM150803(2-(3-((4-Amino-2-methylpyrimidin-5-yl)methyl)pheny...)copy SMILEScopy InChI
Affinity DataKd:  528nMAssay Description:Purified ThiT was diluted in buffer E to a concentration of ~50 nM in a final volume of 800 無. The substrates were added in 1 無 steps. Using an exc...More data for this Ligand-Target Pair
TargetThiamine transporter ThiT(Lactococcus lactis (Firmicutes))
University of Groningen

LigandPNGBDBM150802((4-((4-Amino-2-methylpyrimidin-5-yl)methyl)-3-meth...)copy SMILEScopy InChI
Affinity DataKd:  5.21nMAssay Description:Purified ThiT was diluted in buffer E to a concentration of ~50 nM in a final volume of 800 無. The substrates were added in 1 無 steps. Using an exc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8QJ6PubMed