Compile Data Set for Download or QSAR
Found 13 of ic50 for UniProtKB: P9WG47
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69H6RPubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50330327((R)-7-(3-(2-aminopropan-2-yl)pyrrolidin-1-yl)-9-cy...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HS2PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50131428(1-Cyclopropyl-6-fluoro-8-methoxy-7-(1S,7aS)-octahy...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HS2PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50117914(1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase AMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM93038(Diospyrin)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69H6RPubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50107009(5-Hydroxy-7-methyl-[1,4]naphthoquinone | 5-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69H6RPubMed
TargetDNA gyrase subunit A/B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP)

Curated by ChEMBL
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase supercoiling activity using relaxed pBR322 as substrate after 30 mins by agarose gel electrophore...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM93039(Neodiospyrin)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69H6RPubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM50131445((3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HS2PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM93040(Isodiospyrin | MAR-UNI-c84db004-17)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69H6RPubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM93041(Shinanolone)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69H6RPubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
John Innes Centre

LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Mycobacterium tuberculosis gyrase supercoiling, relaxation, and decatenation assays were carried out as described previously.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69H6RPubMed