Affinity DataIC50: 0nMAssay Description:Concentration required to inhibit Lactobacillus casei derived Dihydrofolate reductase activity by 50%More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Compound was tested for the inhibition of dihydrofolate reductase in Bovine liverMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity of the compound was determined against dihydrofolate reductase in mammalians.(high potency)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Compound was tested for the inhibition of dihydrofolate reductase in Bovine liverMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of MTX-resistant Lactobacillus casei dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Lactobacillus casei ATCC 7469 dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.52nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus casei.More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Compound was tested for the inhibition of dihydrofolate reductase in Bovine liverMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Concentration of the compound required to inhibit L. casei derived Dihydrofolate reductase activity by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Concentration of the compound required to inhibit L. casei derived Dihydrofolate reductase activity by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Concentration of the compound required to inhibit L. casei derived Dihydrofolate reductase activity by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Lactobacillus casei DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.98nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Lactobacillus casei DHFRMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:inhibitory concentration of the compound against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Inhibition of DHFR in Lactobacillus casei using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition by spectrofluoromet...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Concentration required for 50% inhibition against dihydrofolate reductase of L. caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against dihydrofolate reductase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 2)More data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Ability to inhibit Lactobacillus casei dihydrofolate reductase in vitro was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of Dihydrofolate reductase activity against Lactobacillus casei enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR)derived from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of Dihydrofolate reductase activity against Lactobacillus casei enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of Dihydrofolate reductase activity against Lactobacillus casei enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 4)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 3)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Concentration of the compound required to inhibit L. casei derived Dihydrofolate reductase activity by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 15.9nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 2)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 4)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 5)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 6)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 2)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 4)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 3)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of MTX-resistant Lactobacillus casei dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 5)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Lactobacillus casei (lcDHFR)More data for this Ligand-Target Pair
