Compile Data Set for Download or QSAR
Found 174 of kd for UniProtKB: P33981
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569991(CHEMBL4877547)copy SMILES
Affinity DataKd:  0.0710nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569978(CHEMBL4845775)copy SMILES
Affinity DataKd:  0.120nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569979(CHEMBL4875028)copy SMILES
Affinity DataKd:  0.150nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569990(CHEMBL4858486)copy SMILES
Affinity DataKd:  0.170nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569989(CHEMBL4870223)copy SMILES
Affinity DataKd:  0.170nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569977(CHEMBL4846040)copy SMILES
Affinity DataKd:  0.200nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569988(CHEMBL4869527)copy SMILES
Affinity DataKd:  0.290nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569981(CHEMBL4868353)copy SMILES
Affinity DataKd:  0.300nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569975(CHEMBL4860430)copy SMILES
Affinity DataKd:  0.410nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569984(CHEMBL4866294)copy SMILES
Affinity DataKd:  0.410nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569976(CHEMBL4867504)copy SMILES
Affinity DataKd:  0.5nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569980(CHEMBL4873395)copy SMILES
Affinity DataKd:  0.560nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569971(CHEMBL4869142)copy SMILES
Affinity DataKd:  0.630nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569969(CHEMBL4857210)copy SMILES
Affinity DataKd:  0.700nMAssay Description:Binding affinity to human TTK expressed in bacterial expression system assessed as dissociation constant at 100 nM by biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128PRPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569969(CHEMBL4857210)copy SMILES
Affinity DataKd:  0.710nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569974(CHEMBL4861308)copy SMILES
Affinity DataKd:  0.720nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50579637(CHEMBL4878958)copy SMILES
Affinity DataKd:  0.900nMAssay Description:Binding affinity to TTK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7F91PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569982(CHEMBL4859914)copy SMILES
Affinity DataKd:  1.10nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569985(CHEMBL4874692)copy SMILES
Affinity DataKd:  1.5nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569970(CHEMBL4850608)copy SMILES
Affinity DataKd:  2.80nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569973(CHEMBL4863607)copy SMILES
Affinity DataKd:  3.90nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569972(CHEMBL4853778)copy SMILES
Affinity DataKd:  4.20nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM253941(US9464092, GG | US9527857, GG)copy SMILEScopy InChI
Affinity DataKd:  4.20nMAssay Description:Binding affinity to TTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4T3TPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569983(CHEMBL4870731)copy SMILES
Affinity DataKd:  6.10nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI
Affinity DataKd:  6.5nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI
Affinity DataKd:  6.5nMAssay Description:Binding affinity to TTKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569986(CHEMBL4853433)copy SMILES
Affinity DataKd:  7.90nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569968(CHEMBL4859127)copy SMILES
Affinity DataKd:  9.30nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)copy SMILEScopy InChI
Affinity DataKd:  22nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM36486(9-Cyclopentyl-2-(2-ethoxy-4-(4-hydroxypiperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 145nM Kd:  26nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7T57PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50355499(CHEMBL1908395 | CHEMBL1908842)copy SMILEScopy InChI
Affinity DataKd:  34nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM482158(BDBM50242742 | TAE684)copy SMILEScopy InChI
Affinity DataKd:  50nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataKd:  61nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataKd:  61nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705)copy SMILEScopy InChI
Affinity DataKd:  61nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60MFNPCBioAssay
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataKd:  63nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataKd:  63nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataKd:  63nMAssay Description:Binding affinity to TTKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataKd:  63nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60MFNPCBioAssay
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM27817(2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...)copy SMILEScopy InChI
Affinity DataKd:  76nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50131843(CHEMBL3633152)copy SMILEScopy InChI
Affinity DataKd:  81nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1ZPNPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50024294(SP-600125)copy SMILEScopy InChI
Affinity DataKd:  98nMAssay Description:Average Binding Constant for TTK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69J3TPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataKd:  100nMAssay Description:Average Binding Constant for TTK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69J3TPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50355496(CHEMBL1908397)copy SMILEScopy InChI
Affinity DataKd:  110nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50569992(CHEMBL4853927)copy SMILES
Affinity DataKd:  145nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8C33PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)copy SMILEScopy InChI
Affinity DataKd:  150nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)copy SMILEScopy InChI
Affinity DataKd:  150nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60MFNPCBioAssay
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)copy SMILEScopy InChI
Affinity DataKd:  150nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)copy SMILEScopy InChI
Affinity DataKd:  180nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)copy SMILEScopy InChI
Affinity DataKd:  180nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60MFNPCBioAssay
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