Affinity DataKd: 0.0710nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.120nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.150nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.170nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.170nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.290nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.300nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.410nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.410nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.5nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.560nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.630nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.700nMAssay Description:Binding affinity to human TTK expressed in bacterial expression system assessed as dissociation constant at 100 nM by biochemical assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.710nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.720nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 0.900nMAssay Description:Binding affinity to TTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 2.80nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 3.90nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Binding affinity to TTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 6.10nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 6.5nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 6.5nMAssay Description:Binding affinity to TTKMore data for this Ligand-Target Pair
Affinity DataKd: 7.90nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 9.30nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 22nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 145nM Kd: 26nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
Affinity DataKd: 34nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 61nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 63nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 63nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 63nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 76nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 81nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
Affinity DataKd: 98nMAssay Description:Average Binding Constant for TTK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Average Binding Constant for TTK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 110nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 145nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 150nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair