null
SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n([C@@H]3CC[C@@H](CC3)NC(=O)C3CCCCC3)c2n1)N1CCN(C)CC1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50569979
Affinity DataKd: 0.150nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant full-length human TTK using MBP as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting b...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to wild-type human partial length PIK3CD (R108 to Q1044 residues) expressed in HEK293 cells by active site-directed competition bind...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to wild-type human partial length IRAK1 (R194 to S712 residues) expressed in mammalian expression system by active site-directed com...More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to wild-type human full length MARK3 (M1 to L729 residues) expressed in bacterial expression system by measuring active site-directe...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to human partial length PIK3C2G (M1 to I1446 residues) expressed in mammalian expression system by active site-directed competition ...More data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity to wild-type human partial length DAPK3 (M1 to A277 residues) expressed in bacterial expression system by measuring active site-dire...More data for this Ligand-Target Pair