Compile Data Set for Download or QSAR
Found 46 Enz. Inhib. hit(s) with all data for entry = 1132
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310899(4-[4-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310892(N-(2-methoxyethyl)-4-(6-methyl-7-oxo-1H-pyrrolo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310896(7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310895(3-methyl-7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILES
Affinity DataIC50: 31nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310905(2-methyl-7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILES
Affinity DataIC50: 36nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310889(4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310898(N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310902(6-methyl-4-[4-(1-methyl-4-piperidyl)phenyl]-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310911(6-methyl-4-(2-methyl-3,4-dihydro-1H-isoquinolin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310880(7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4...)copy SMILES
Affinity DataIC50: 58nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310915(N-benzyl-4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310903(6-methyl-4-[4-[(1-methyl-4-piperidyl)methyl]phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310910(4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310879(2-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-5...)copy SMILES
Affinity DataIC50: 81nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310884(4-[4-(3-fluoroazetidine-1-carbonyl)phenyl]-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310894(US10150767, Example 6 | tert-butyl N-[4-(6-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310913(N-methyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310878(3-isopropyl-6-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyr...)copy SMILES
Affinity DataIC50: 110nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310876(3-methyl-6-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILES
Affinity DataIC50: 110nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310874(US10150767, Example 4 | tert-butyl 6-(6-methyl-7-o...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310901(6-cyclopropyl-4-(4-(2-hydroxypropan-2-yl)phenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310893(US10150767, Example 5 | tert-butyl 7-(6-methyl-7-o...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310912(3-(2,6-dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310909(4-[4-(3,3-difluoroazetidine-1-carbonyl)phenyl]-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310882(3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)be...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310886(6-methyl-4-[4-(4-methylpiperidine-1-carbonyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310877(4-methyl-7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILES
Affinity DataIC50: 170nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310904(3-methoxy-N-[4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310881(3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)be...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310891(N-(cyanomethyl)-N-methyl-4-(6-methyl-7-oxo-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310873(6-methyl-4-(2-oxoindolin-5-yl)-1H-pyrrolo[2,3-c]py...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310897(N,N-dimethyl-3-(7-oxo-6-propyl-1H-pyrrolo[2,3-c]py...)copy SMILEScopy InChI
Affinity DataIC50: 238nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310908(6-methyl-4-(4-(4-methyl-3-oxopiperazine-1-carbonyl...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310886(6-methyl-4-[4-(4-methylpiperidine-1-carbonyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310885(6-methyl-4-[4-(pyrrolidine-1-carbonyl)phenyl]-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310875(8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyr...)copy SMILES
Affinity DataIC50: 310nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310887(4-[4-(4-acetylpiperazine-1-carbonyl)phenyl]-6-meth...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310890(N-methyl-4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310914(6-methyl-4-[4-(morpholine-4-carbonyl)phenyl]-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310917(6-methyl-4-[3-[(1-methyl-4-piperidyl)methyl]phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310872(6-methyl-4-phenyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-o...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310916(6-methyl-4-[3-(1-methyl-4-piperidyl)phenyl]-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310883(4-[4-(hydroxymethyl)phenyl]-6-methyl-1H-pyrrolo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310906(N,N-dimethyl-4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetChromatin remodeling regulator CECR2 [424-538](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310907(3-(6-ethyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent
TargetBromodomain-containing protein 9 [134-239](Homo sapiens (Human))
Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent
LigandPNGBDBM310900(4-[4-(1-hydroxy-1-methyl-ethyl)phenyl]-6-isopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V98B5WUS Patent