Compile Data Set for Download or QSAR
Found 145 Enz. Inhib. hit(s) with all data for entry = 1237
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10351(1-(4-Methoxybenzyl)-5-(2-(pyridin-3-yl-oxymethyl)-...)copy SMILEScopy InChI
Affinity DataKi:  4.40nM IC50: 3.90nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10352(1-(4-Methylthiobenzyl)-5-(2-(pyridin-3-yl-oxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-8(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10357((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10350(1-Benzyl-5-(2-(pyridin-3-yl-oxymethyl)-pyrrolidine...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10347((S)-1-(6-Fluoropyridin-2-yl-methyl)-5-(2-phenoxyme...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-1(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10355((3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-(4-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10341((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidi...)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10353(1-(4-Fluorobenzyl)-5-(2-(pyridin-3-yl-oxymethyl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10343((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-azetidin...)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10337((S)-1-(6-Fluoro-pyridin-2-yl-methyl)-5-(2-phenoxym...)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10344((S)-1-(2-Fluorobenzyl)-5-(2-phenoxymethyl-azetidin...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10340((S)-1-Benzyl-5-(2-phenoxymethyl-azetidine-1-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10335((S)-1-(6-Fluoropyridin-3-yl-methyl)-5-(2-phenoxyme...)copy SMILEScopy InChI
Affinity DataIC50: 10.3nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10345((S)-1-(6-Fluoropyridin-3-ylmethyl)-5-(2-phenoxymet...)copy SMILEScopy InChI
Affinity DataIC50: 10.9nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10342((S)-1-(4-Methylthiobenzyl)-5-(2-phenoxymethyl-azet...)copy SMILEScopy InChI
Affinity DataIC50: 11.3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10333(4-[(2,3-dioxo-5-{[(2S)-2-(phenoxymethyl)pyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10331((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...)copy SMILEScopy InChI
Affinity DataIC50: 12.1nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10323((S)-1-Benzyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)copy SMILEScopy InChI
Affinity DataIC50: 12.2nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10332((S)-1-(4-Methylthiobenzyl)-5-(2-phenoxymethyl-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 12.4nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10334((S)-1-(4-Hydroxybenzyl)-5-(2-phenoxymethyl-pyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 13.5nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10350(1-Benzyl-5-(2-(pyridin-3-yl-oxymethyl)-pyrrolidine...)copy SMILEScopy InChI
Affinity DataIC50: 14.1nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10335((S)-1-(6-Fluoropyridin-3-yl-methyl)-5-(2-phenoxyme...)copy SMILEScopy InChI
Affinity DataIC50: 14.5nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10330((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-pyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 14.5nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10353(1-(4-Fluorobenzyl)-5-(2-(pyridin-3-yl-oxymethyl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 15.1nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10351(1-(4-Methoxybenzyl)-5-(2-(pyridin-3-yl-oxymethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 15.1nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10345((S)-1-(6-Fluoropyridin-3-ylmethyl)-5-(2-phenoxymet...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10354(5-(2-(Pyridin-4-yl-oxymethyl)-pyrrolidine-1-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 20.4nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10343((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-azetidin...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10336((S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxym...)copy SMILEScopy InChI
Affinity DataIC50: 21.3nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10330((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-pyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 21.8nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10337((S)-1-(6-Fluoro-pyridin-2-yl-methyl)-5-(2-phenoxym...)copy SMILEScopy InChI
Affinity DataIC50: 22.2nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10347((S)-1-(6-Fluoropyridin-2-yl-methyl)-5-(2-phenoxyme...)copy SMILEScopy InChI
Affinity DataIC50: 22.7nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10331((S)-1-(4-Fluorobenzyl)-5-(2-phenoxymethyl-pyrrolid...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10341((S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-azetidi...)copy SMILEScopy InChI
Affinity DataIC50: 23.2nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10349(1-Methyl-5-(2-(pyridin-3-yl-oxymethyl)-pyrrolidine...)copy SMILEScopy InChI
Affinity DataIC50: 23.3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10352(1-(4-Methylthiobenzyl)-5-(2-(pyridin-3-yl-oxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 23.3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10344((S)-1-(2-Fluorobenzyl)-5-(2-phenoxymethyl-azetidin...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10342((S)-1-(4-Methylthiobenzyl)-5-(2-phenoxymethyl-azet...)copy SMILEScopy InChI
Affinity DataIC50: 26.7nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10323((S)-1-Benzyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10346((S)-1-(2-Fluoropyridin-4-yl-methyl)-5-(2-phenoxyme...)copy SMILEScopy InChI
Affinity DataIC50: 29.2nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10340((S)-1-Benzyl-5-(2-phenoxymethyl-azetidine-1-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 29.5nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10333(4-[(2,3-dioxo-5-{[(2S)-2-(phenoxymethyl)pyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 34.8nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10332((S)-1-(4-Methylthiobenzyl)-5-(2-phenoxymethyl-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10334((S)-1-(4-Hydroxybenzyl)-5-(2-phenoxymethyl-pyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-7(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10336((S)-1-(2-Fluoro-pyridin-4-yl-methyl)-5-(2-phenoxym...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10348(5-(2-(Pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 58.3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-6(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10356((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 60.5nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
TargetCaspase-3(Homo sapiens (Human))
Washington University School of Medicine

LigandPNGBDBM10339((S)-1-Methyl-5-(2-phenoxymethyl-azetidine-1-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 91.7nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40SDNPubMed
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