Compile Data Set for Download or QSAR
Found 111 Enz. Inhib. hit(s) with all data for entry = 50006636
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051910((R)-4-Amino-5-(4-{[(2,4-diamino-pyrido[2,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051922((R)-4-Amino-5-{4-[(2,4-diamino-pyrido[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051910((R)-4-Amino-5-(4-{[(2,4-diamino-pyrido[2,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051922((R)-4-Amino-5-{4-[(2,4-diamino-pyrido[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051920(2,4-DIAMINO-6-[N-(3',4',5'-TRIMETHOXYBENZYL)-N-MET...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051915(CHEMBL32708 | N*6*-(2,5-Dimethoxy-benzyl)-pyrido[2...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051923(2,4-DIAMINO-6-[N-(3',5'-DIMETHOXYBENZYL)-N-METHYLA...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory activity of the compound against Toxoplasma gondii dihydrofolate reductase (in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051918(CHEMBL35222 | N*6*-Methyl-N*6*-(2,3,4-trimethoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibitory activity of the compound against Toxoplasma gondii dihydrofolate reductase (in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051918(CHEMBL35222 | N*6*-Methyl-N*6*-(2,3,4-trimethoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity of the compound against Toxoplasma gondii dihydrofolate reductase (in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051923(2,4-DIAMINO-6-[N-(3',5'-DIMETHOXYBENZYL)-N-METHYLA...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibitory activity of the compound against Toxoplasma gondii dihydrofolate reductase (in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051918(CHEMBL35222 | N*6*-Methyl-N*6*-(2,3,4-trimethoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051930(CHEMBL33038 | N*6*-Benzyl-N*6*-methyl-pyrido[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051920(2,4-DIAMINO-6-[N-(3',4',5'-TRIMETHOXYBENZYL)-N-MET...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051930(CHEMBL33038 | N*6*-Benzyl-N*6*-methyl-pyrido[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibitory activity of the compound against Toxoplasma gondii dihydrofolate reductase (in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against recombinant human dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051919(CHEMBL33208 | N*6*-(3,4,5-Trimethoxy-benzyl)-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibitory activity of the compound against recombinant lc dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMedMMDB
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051920(2,4-DIAMINO-6-[N-(3',4',5'-TRIMETHOXYBENZYL)-N-MET...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051922((R)-4-Amino-5-{4-[(2,4-diamino-pyrido[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibitory activity of the compound against recombinant lc dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051930(CHEMBL33038 | N*6*-Benzyl-N*6*-methyl-pyrido[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051923(2,4-DIAMINO-6-[N-(3',5'-DIMETHOXYBENZYL)-N-METHYLA...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051923(2,4-DIAMINO-6-[N-(3',5'-DIMETHOXYBENZYL)-N-METHYLA...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051918(CHEMBL35222 | N*6*-Methyl-N*6*-(2,3,4-trimethoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051912(CHEMBL32266 | N*6*-(3,5-Dimethoxy-benzyl)-pyrido[2...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051915(CHEMBL32708 | N*6*-(2,5-Dimethoxy-benzyl)-pyrido[2...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051930(CHEMBL33038 | N*6*-Benzyl-N*6*-methyl-pyrido[2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051910((R)-4-Amino-5-(4-{[(2,4-diamino-pyrido[2,3-d]pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibitory activity of the compound against recombinant lc dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051929(CHEMBL32583 | N*6*-[1-(3,4,5-Trimethoxy-phenyl)-et...)copy SMILEScopy InChI
Affinity DataIC50: 194nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051924(CHEMBL32754 | N*6*-(2,4,6-Trimethoxy-benzyl)-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051931(CHEMBL32635 | N*6*-Naphthalen-1-ylmethyl-pyrido[2,...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051927(CHEMBL33136 | N*6*-Phenethyl-pyrido[2,3-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051915(CHEMBL32708 | N*6*-(2,5-Dimethoxy-benzyl)-pyrido[2...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051922((R)-4-Amino-5-{4-[(2,4-diamino-pyrido[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against recombinant human dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051919(CHEMBL33208 | N*6*-(3,4,5-Trimethoxy-benzyl)-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051915(CHEMBL32708 | N*6*-(2,5-Dimethoxy-benzyl)-pyrido[2...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
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