Compile Data Set for Download or QSAR
Found 15 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50051913'
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38RZ9PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))TBA
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
In DepthDetails MMDB
TargetDihydrofolate reductase(Homo sapiens (Human))TBA
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondii (tgDHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1HQZPubMedMMDB
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity of the compound against recombinant sf dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMedMMDB
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of dihydrofolate reductase from rat liver.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38RZ9PubMedMMDB
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03PTPubMedMMDB
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40TQ3PubMedMMDB
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38RZ9PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40TQ3PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP03PTPubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase (in 90 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity of the compound against recombinant ec dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibitory activity of the compound against recombinant lc dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))TBA
LigandPNGBDBM50051913(CHEMBL32113 | N*6*-(2,5-Dimethoxy-benzyl)-N*6*-met...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibitory activity against recombinant human dihydrofolate reductase(in 50 microM dihydrofolic acid)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0F8NPubMedMMDB