Compile Data Set for Download or QSAR
Found 73 Enz. Inhib. hit(s) with all data for entry = 50010803
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50230993((2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]penta...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098940(8-Fluoro-3-(4-fluoro-phenyl)-3,4-dihydro-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50230993((2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]penta...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against nitric oxide synthesis in intact DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50230993((2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]penta...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098942(3,4-Dihydro-isoquinolin-1-ylamine | CHEMBL7891)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098930(3-Ethynyl-3,4-dihydro-isoquinolin-1-ylamine | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098932(8-Fluoro-3-phenyl-3,4-dihydro-isoquinolin-1-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098930(3-Ethynyl-3,4-dihydro-isoquinolin-1-ylamine | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098929(3-Furan-2-yl-3,4-dihydro-isoquinolin-1-ylamine | C...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098929(3-Furan-2-yl-3,4-dihydro-isoquinolin-1-ylamine | C...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098934(3-Cyclopropyl-3,4-dihydro-isoquinolin-1-ylamine | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098934(3-Cyclopropyl-3,4-dihydro-isoquinolin-1-ylamine | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098942(3,4-Dihydro-isoquinolin-1-ylamine | CHEMBL7891)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098933(3-Thiophen-2-yl-3,4-dihydro-isoquinolin-1-ylamine ...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098932(8-Fluoro-3-phenyl-3,4-dihydro-isoquinolin-1-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098931(4,5-Dihydro-3H-benzo[c]azepin-1-ylamine | CHEMBL26...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098933(3-Thiophen-2-yl-3,4-dihydro-isoquinolin-1-ylamine ...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098930(3-Ethynyl-3,4-dihydro-isoquinolin-1-ylamine | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098941(3-Methyl-3,4-dihydro-isoquinolin-1-ylamine | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098934(3-Cyclopropyl-3,4-dihydro-isoquinolin-1-ylamine | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098941(3-Methyl-3,4-dihydro-isoquinolin-1-ylamine | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098939(3-Thiazol-2-yl-3,4-dihydro-isoquinolin-1-ylamine |...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50207159(2-aminoguanidine | 2-azanylguanidine | AMINOGUANID...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098927(5-Fluoro-3-(4-fluoro-phenyl)-3,4-dihydro-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098929(3-Furan-2-yl-3,4-dihydro-isoquinolin-1-ylamine | C...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098935(8-Chloro-3-(4-fluoro-phenyl)-3,4-dihydro-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098927(5-Fluoro-3-(4-fluoro-phenyl)-3,4-dihydro-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098928(3-(4-Fluoro-phenyl)-3,4-dihydro-isoquinolin-1-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098948(8-Chloro-3-phenyl-3,4-dihydro-isoquinolin-1-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50207159(2-aminoguanidine | 2-azanylguanidine | AMINOGUANID...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098933(3-Thiophen-2-yl-3,4-dihydro-isoquinolin-1-ylamine ...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098939(3-Thiazol-2-yl-3,4-dihydro-isoquinolin-1-ylamine |...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098938(6-Fluoro-3-(4-fluoro-phenyl)-3,4-dihydro-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098936(3-Phenyl-3,4-dihydro-isoquinolin-1-ylamine | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098928(3-(4-Fluoro-phenyl)-3,4-dihydro-isoquinolin-1-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098947(3-(3-Fluoro-phenyl)-3,4-dihydro-isoquinolin-1-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098943(3,3-Dimethyl-3,4-dihydro-isoquinolin-1-ylamine | C...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098947(3-(3-Fluoro-phenyl)-3,4-dihydro-isoquinolin-1-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098931(4,5-Dihydro-3H-benzo[c]azepin-1-ylamine | CHEMBL26...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098936(3-Phenyl-3,4-dihydro-isoquinolin-1-ylamine | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098944(3-(2-Fluoro-phenyl)-3,4-dihydro-isoquinolin-1-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098940(8-Fluoro-3-(4-fluoro-phenyl)-3,4-dihydro-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098941(3-Methyl-3,4-dihydro-isoquinolin-1-ylamine | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by inducible NOS (i NOS) from human DLD-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098939(3-Thiazol-2-yl-3,4-dihydro-isoquinolin-1-ylamine |...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Ability to inhibit conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K073JZPubMed
Displayed 1 to 50 (of 73 total ) | Next | Last >>
Jump to: